3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone

Base Information

Chemical Name:3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone
CAS No.:389574-41-8
Molecular Formula:C₂₀H₂₉N₃O₃
Molecular Weight:359.469
Hs Code.:

Synonyms:3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone

Suppliers and Price of 3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone

There total 3 articles about 3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 389574-39-4
3-[3-(Dimethylamino)propyl]sydnone

: (E)-3-Methyl-6-phenylhex-5-enal

: 389574-41-8
3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone

Guidance literature:: 3-[3-(Dimethylamino)propyl]sydnone; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

(E)-3-Methyl-6-phenylhex-5-enal; In tetrahydrofuran; hexane; at 20 ℃; for 4h;
DOI:10.1055/s-2001-17517

Reference yield:

: 7568-53-8
ethyl N-[3-(N′,N′-dimethylamino)propyl]glycinate

: 389574-41-8
3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone

Guidance literature:: Multi-step reaction with 2 steps

1.1: NaOH / methanol / 2 h / Heating

1.2: aq. NaNO₂; HCl / 0.75 h

1.3: 42 percent / Ac₂O / H₂O / 2 h / 90 °C

2.1: BuLi / hexane; tetrahydrofuran / 0.5 h / -78 °C

2.2: 65 percent / tetrahydrofuran; hexane / 4 h / 20 °C

With sodium hydroxide; n-butyllithium; In tetrahydrofuran; methanol; hexane;
DOI:10.1055/s-2001-17517

Reference yield:

: 109-55-7
1-amino-3-(dimethylamino)propane

: 389574-41-8
3-[3-(Dimethylamino)propyl]-4-[(1-hydroxy-3-methyl-6-phenyl)-5-hexyl]sydnone

Guidance literature:: Multi-step reaction with 3 steps

1.1: 68 percent / K₂CO₃ / benzene / 10 h

2.1: NaOH / methanol / 2 h / Heating

2.2: aq. NaNO₂; HCl / 0.75 h

2.3: 42 percent / Ac₂O / H₂O / 2 h / 90 °C

3.1: BuLi / hexane; tetrahydrofuran / 0.5 h / -78 °C

3.2: 65 percent / tetrahydrofuran; hexane / 4 h / 20 °C

With sodium hydroxide; n-butyllithium; potassium carbonate; In tetrahydrofuran; methanol; hexane; benzene;
DOI:10.1055/s-2001-17517