Camobucol

Base Information

Chemical Name:Camobucol
CAS No.:216167-92-9
Molecular Formula:C33H50 O4 S2
Molecular Weight:574.89
Hs Code.:
UNII:FZ7798X3IR
DSSTox Substance ID:DTXSID70176004
Wikidata:Q27278339
NCI Thesaurus Code:C72724
ChEMBL ID:CHEMBL2104958
Mol file:216167-92-9.mol

Synonyms:(4-((1-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)thio)-1-methylethyl)thio)-2,6-bis(1,1-dimethylethyl)phenoxy)acetic acid;AGIX 4207;AGIX-4207;AGIX4207;camobucol;ylgucpd100bdh

Suppliers and Price of Camobucol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
AGIX-4207 95.00%
5MG
$ 496.14

Total 7 raw suppliers

Chemical Property of Camobucol

Chemical Property:

Melting Point:164-165 °C
Boiling Point:622.6±55.0 °C(Predicted)
PKA:3.23±0.10(Predicted)
PSA：117.36000
Density:1.11±0.1 g/cm3(Predicted)
LogP:9.66610
XLogP3:11.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:574.31505242
Heavy Atom Count:39
Complexity:764

Purity/Quality:

97% ^*data from raw suppliers

AGIX-4207 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SC(C)(C)SC2=CC(=C(C(=C2)C(C)(C)C)OCC(=O)O)C(C)(C)C
Uses Treatment of inflammatory diseases.

Technology Process of Camobucol

There total 2 articles about Camobucol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

: 216168-57-9
{2,6-di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxyphenylsulfanyl)-1-methylethylsulfanyl]phenoxy}acetic acid ethyl ester

: 216167-92-9
2-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic acid

Guidance literature:: {2,6-di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-hydroxyphenylsulfanyl)-1-methylethylsulfanyl]phenoxy}acetic acid ethyl ester; With lithium hydroxide; water; In tetrahydrofuran; methanol; for 1h;

With hydrogenchloride; In tetrahydrofuran; methanol; water;

Reference yield:

: 23288-49-5
(4,4'-isopropylidenedithio)bis[2,6-di-tert-butylphenol]

: 216167-92-9
2-[4-[[1-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 160 mg / KF/Al₂O₃ / dimethylformamide / 24 h

2: 90 mg / aq. LiOH / tetrahydrofuran; methanol

With lithium hydroxide; aluminum oxide; potassium fluoride; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm049685u