methyl 2-(2-chloroacetamido)-3-methylbenzoate

Base Information

• Chemical Name: methyl 2-(2-chloroacetamido)-3-methylbenzoate
• CAS No.: 77093-79-9
• Molecular Formula: C₁₁H₁₂ClNO₃
• Molecular Weight: 241.674
• Mol file: 77093-79-9.mol

Synonyms:2'-carbomethoxy-6'-methyl-2-chloroacetanilide

Chemical Property of methyl 2-(2-chloroacetamido)-3-methylbenzoate

Chemical Property:

• Solubility.: Chloroform, DCM, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

2-[(2-Chloroacetyl)amino]-3-methylbenzoicAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-[(2-Chloroacetyl)amino]-3-methylbenzoic Acid Methyl Ester is an intermediate in the synthesis of Tolycaine Hydrochloride (T536625), an anesthetic drug.

Technology Process of methyl 2-(2-chloroacetamido)-3-methylbenzoate

There total 2 articles about methyl 2-(2-chloroacetamido)-3-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

methyl 2-amino-3-methylbenzoate (22223-49-0) + sodium carbonate (497-19-8) + chloroacetyl chloride (79-04-9) → 2'-carbomethoxy-6'-methyl-2-chloroacetanilide (77093-79-9)

Guidance literature:

In dichloromethane;

Reference yield:

→ 2'-carbomethoxy-6'-methyl-2-chloroacetanilide (77093-79-9)

Guidance literature:

Chloressigsaeure, entspr. Aminoester;

upstream raw materials:

methyl 2-amino-3-methylbenzoate

sodium carbonate

chloroacetyl chloride