3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione

Base Information

Chemical Name:3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione
CAS No.:219708-53-9
Molecular Formula:C₁₉H₂₉NO₅Si
Molecular Weight:379.528
Hs Code.:

Synonyms:3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione

Suppliers and Price of 3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione

There total 3 articles about 3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 2346-26-1
2,4-oxazolidinedione

: 219708-51-7
3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propan-1-ol

: 219708-53-9
3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; 1.) ice-cooling, 10 min, 2.) r.t. 12 h;
DOI:10.1039/a804666b

Reference yield:

: 60779-18-2
Methyl-o-carbomethoxymethoxyphenylacetat

: 219708-53-9
3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 65 percent / LiAlH₄ / diethyl ether / 1.) 10 h, 2.) reflux, 1.5 h

2: 88 percent / NaH / tetrahydrofuran / 1.) r.t., 1 h, 2.) r.t., 8 h

3: 79 percent / Ph₃P, diisopropyl azodicarboxylate / tetrahydrofuran / 1.) ice-cooling, 10 min, 2.) r.t. 12 h

With lithium aluminium tetrahydride; di-isopropyl azodicarboxylate; sodium hydride; triphenylphosphine; In tetrahydrofuran; diethyl ether;
DOI:10.1039/a804666b

Reference yield:

: 20730-59-0
2-(2-methoxyphenyl)-1,3-propanediol

: 219708-53-9
3-[3-(tert-Butyl-dimethyl-silanyloxy)-2-(2-methoxy-phenyl)-propyl]-oxazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / NaH / tetrahydrofuran / 1.) r.t., 1 h, 2.) r.t., 8 h

2: 79 percent / Ph₃P, diisopropyl azodicarboxylate / tetrahydrofuran / 1.) ice-cooling, 10 min, 2.) r.t. 12 h

With di-isopropyl azodicarboxylate; sodium hydride; triphenylphosphine; In tetrahydrofuran;
DOI:10.1039/a804666b