4,4,4-Trifluoro-1-phenylbutan-2-one

Base Information

Chemical Name:4,4,4-Trifluoro-1-phenylbutan-2-one
CAS No.:121194-37-4
Molecular Formula:C₁₀H₉F₃O
Molecular Weight:202.176
Hs Code.:
European Community (EC) Number:862-299-1
DSSTox Substance ID:DTXSID101292265
Nikkaji Number:J1.647.086D

Synonyms:4,4,4-TRIFLUORO-1-PHENYLBUTAN-2-ONE;121194-37-4;SCHEMBL1033376;DTXSID101292265;AKOS010652249;AB70560;4,4,4-Trifluoro-1-phenyl-2-butanone;CS-0241558;EN300-2339919

Suppliers and Price of 4,4,4-Trifluoro-1-phenylbutan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 4,4,4-Trifluoro-1-phenylbutan-2-one

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:202.06054939
Heavy Atom Count:14
Complexity:192

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(=O)CC(F)(F)F

Technology Process of 4,4,4-Trifluoro-1-phenylbutan-2-one

There total 4 articles about 4,4,4-Trifluoro-1-phenylbutan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 887144-94-7
Togni's reagent II

: 40886-84-8
4-phenylbut-2-ynoic acid

: 121194-37-4
4,4,4-Trifluoro-1-phenyl-butan-2-one

Guidance literature:: With copper(II) gluconate; In tetrachloromethane; water; at 80 ℃; for 12h;
DOI:10.1039/c3sc51613j

Reference yield: 14.0%

: 201230-82-2
carbon monoxide

: 149846-93-5,128746-89-4,503311-61-3
1-phenyl-4,4,4-trifluorobut-2-yn-1-ol

: 121194-37-4
4,4,4-Trifluoro-1-phenyl-butan-2-one

Guidance literature:: With hydrogen; palladium diacetate; triphenylphosphine; In dichloromethane; at 85 ℃; for 30h;
DOI:10.1016/S0040-4039(01)02006-8

Reference yield:

: 120779-90-0
3-(tert-Butyl-methyl-hydrazono)-1,1,1-trifluoro-4-phenyl-butan-2-one

: 121194-37-4
4,4,4-Trifluoro-1-phenyl-butan-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / pyridine, trifluoroacetic anhydride / 5 h

2: 62 percent / CH₃I / ethanol / 18 h / Heating

With pyridine; trifluoroacetic anhydride; methyl iodide; In ethanol;
DOI:10.1055/s-1989-27144