methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate

Base Information

Chemical Name:methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate
CAS No.:937399-84-3
Molecular Formula:C₁₈H₂₂F₃NO₅
Molecular Weight:389.372
Hs Code.:

Synonyms:methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate

Suppliers and Price of methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate

There total 1 articles about methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 156006-28-9
3,4,5-trifluorophenylmagnesium bromide

: 183890-36-0
(R)-6-oxopiperidine-1,2-dicarboxylic acid 1-tertiary butyl ester 2-methyl ester

: 937399-84-3
methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate

Guidance literature:: 3,4,5-trifluorophenylmagnesium bromide; (R)-6-oxopiperidine-1,2-dicarboxylic acid 1-tertiary butyl ester 2-methyl ester; In tetrahydrofuran; diethyl ether; at -40 - 20 ℃; for 6h;

With water; ammonium chloride; In tetrahydrofuran; diethyl ether; ethyl acetate;

Reference yield:

: 937399-84-3
methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate

: 937399-85-4
(2R,6S)-6-(3,4,5-trifluorophenyl)piperidine-2-carboxylic acid methyl ester

Guidance literature:: methyl (R)-2-tert-butoxycarbonylamino-6-oxo-6-(3,4,5-trifluorophenyl)hexanoate; With hydrogenchloride; In ethyl acetate; at 20 ℃; for 14h;

With sodium hydrogencarbonate; In water; ethyl acetate;

With hydrogen; palladium 10% on activated carbon; In ethyl acetate; at 20 ℃; for 6h;