5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine

Base Information

• Chemical Name: 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine
• CAS No.: 1025783-17-8
• Molecular Formula: C₃₄H₃₇N₃O₉
• Molecular Weight: 631.682

Synonyms:5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine

Chemical Property of 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine

Chemical Property:

Purity/Quality:

≥98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine

There total 1 articles about 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine (815632-50-9) + 4,4'-dimethoxytrityl chloride (40615-36-9) → 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine (1025783-17-8)

Guidance literature:

With pyridine; dmap; at 20 ℃; for 3h;

DOI:10.1021/jm701537z

Reference yield: 97.0%

succinic acid anhydride (108-30-5) + 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine (1025783-17-8) → 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine 3'-O-succinate (1025783-24-7)

Guidance literature:

With pyridine; dmap; at 20 ℃;

DOI:10.1021/jm701537z

Reference yield: 84.0%

5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine (1025783-17-8) + N,N,N',N'-tetraisopropyl 2-cyanoethylphosphorodiamidite (102691-36-1) → [5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite (1025783-16-7)

Guidance literature:

With 4,5-dicyano-1H-imidazole; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1021/jm701537z

upstream raw materials:

2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine

4,4'-dimethoxytrityl chloride

Downstream raw materials:

5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine 3'-O-succinate

[5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine]-3'-[(2-cyanoethyl)-N,N-diisopropyl]phosphoramidite

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1025783-17-8 5'-O-(4,4'-dimethoxytrityl)-2'-O-[2-(methylamino)-2-oxoethyl]-5-methyluridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send