2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

Base Information

Chemical Name:2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide
CAS No.:1620051-22-0
Molecular Formula:C₂₉H₃₀N₂O₃
Molecular Weight:454.569
Hs Code.:

Synonyms:2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

Suppliers and Price of 2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

There total 4 articles about 2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 13329-40-3
4-Iodoacetophenone

: 1620050-88-5
N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

: 1620051-22-0
2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

Guidance literature:: With silver(I) acetate; palladium diacetate; In tert-butyl alcohol; at 60 ℃; for 24h; Schlenk technique; Inert atmosphere;
DOI:10.1039/c4cc03615h

Reference yield: 38.0%

: 1620050-88-5
N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

: 99-90-1
para-bromoacetophenone

: 1620051-22-0
2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

Guidance literature:: With palladium diacetate; potassium carbonate; Trimethylacetic acid; In tert-butyl alcohol; at 120 ℃; for 24h; Schlenk technique; Inert atmosphere;
DOI:10.1039/c4cc03615h

Reference yield:

: 52568-28-2
2-(pyridin-2-yl)isopropyl amine

: 1620051-22-0
2,4-bis(4-acetylphenyl)-N-(2-(pyridin-2-yl)propan-2-yl)cyclobutanecarboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 4-methyl-morpholine; isobutyl chloroformate / dichloromethane / 0.5 h / Cooling with ice

1.2: Cooling with ice

2.1: palladium diacetate; silver(I) acetate / tert-butyl alcohol / 24 h / 60 °C / Schlenk technique; Inert atmosphere

With 4-methyl-morpholine; silver(I) acetate; palladium diacetate; isobutyl chloroformate; In dichloromethane; tert-butyl alcohol;
DOI:10.1039/c4cc03615h