(-)-(1R,2S,3R,4S)-2-Benzyloxy-3-bornanol

Base Information

• Chemical Name: (-)-(1R,2S,3R,4S)-2-Benzyloxy-3-bornanol
• CAS No.: 104154-98-5
• Molecular Formula: C₁₇H₂₄O₂
• Molecular Weight: 260.376
• Mol file: 104154-98-5.mol

Synonyms:(-)-(1R,2S,3R,4S)-2-Benzyloxy-3-bornanol

Chemical Property of (-)-(1R,2S,3R,4S)-2-Benzyloxy-3-bornanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(1R,2S,3R,4S)-2-Benzyloxy-3-bornanol

There total 15 articles about (-)-(1R,2S,3R,4S)-2-Benzyloxy-3-bornanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(+)-(1R,2S,3R,4S)-2-Benzyloxy-3-formyl-bornane (110259-75-1) → (-)-(1R,2S,3R,4S)-2-Benzyloxy-3-bornanol (104154-98-5)

Guidance literature:

With potassium hydroxide; In methanol; for 26h; Ambient temperature;

DOI:10.1055/s-1986-31783

Reference yield: 42.0%

2-endo-3-endo camphane-2,3-diol (73522-22-2) + benzyl chloride (100-44-7) → (+)-(1R,2R,3S,4S)-2-benzyloxy-3-hydroxy-1,7,7-trimethylbicyclo<2.2.1>heptane (73440-85-4,89015-58-7,104154-98-5,110312-07-7,110312-08-8) + (1R,2R,3S,4S)-3-Benzyloxy-1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-ol (104154-97-4)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; for 3h; Ambient temperature;

Reference yield: 41.0%

(1R)-(-)-cis-3-hydroxyisoborneol (59599-25-6) + benzyl chloride (100-44-7) → (-)-(1R,2S,3R,4S)-2-Benzyloxy-3-bornanol (104154-98-5) + (+)-(1R,2S,3R,4S)-2-hydroxy-3-benzyloxy-1,7,7-trimethylbicyclo<2.2.1>heptane (73440-88-7)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; for 4h; Ambient temperature;

upstream raw materials:

benzyl bromide

(1R,4S)-3,3-Dimethoxy-bornan-2-one

(R)-camphorquinone

2-endo-3-endo camphane-2,3-diol

Downstream raw materials:

(+)-(1R,2R,3S,4S)-1,2-bis(2-benzyloxy-1,7,7-trimethylbicyclo<2.2.1>hept-3-yloxy)ethane

cyclohexene (2)-1-one-3<(-) (1R, 2S, 3R, 4S)-benzyloxy-3-bornyl>-carboxylate

cyclopentene (2)-1-one-3-<(-) (1R, 2S, 3R, 4S)-2-benzyloxy-3-bornyl> carboxylate

Acrylsaeure-<(1R,2S,3R)-2-benzyloxybornyl>ester