Ethanone, 1-(3-indolizinyl)- (9CI)

Base Information

• Chemical Name: Ethanone, 1-(3-indolizinyl)- (9CI)
• CAS No.: 25314-91-4
• Molecular Formula: C₁₀H₉NO
• Molecular Weight: 159.188
• Mol file: 25314-91-4.mol

Synonyms:Ketone,3-indolizinyl methyl (7CI,8CI); 1-(Indolizin-3-yl)ethanone;3-Acetylpyrrolo[1,2-a]pyridine

Chemical Property of Ethanone, 1-(3-indolizinyl)- (9CI)

Chemical Property:

• Boiling Point: 148 - 149 °C (9.5 mmHg)
• PSA: 21.48000
• LogP: 2.14190

Purity/Quality:

99% ^*data from raw suppliers

1-(3-indolizinyl)-Ethanone 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-(3-indolizinyl)- (9CI)

There total 7 articles about Ethanone, 1-(3-indolizinyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

indolizine (274-40-8) + acetic anhydride (108-24-7) → 3-acetylindolizine (25314-91-4)

Guidance literature:

Heating;

Reference yield: 75.0%

→ 3-acetylindolizine (25314-91-4)

Guidance literature:

Reference yield: 62.0%

2-methyl-1-(2-oxo-propyl)-pyridinium; bromide (75487-74-0) + N,N-dimethylformamide di-tert-butyl acetal (36805-97-7) → 2-methylindolizine (768-18-3) + 3-acetylindolizine (25314-91-4)

Guidance literature:

In N,N-dimethyl-formamide; at 130 ℃; for 0.166667h;

DOI:10.1016/j.tetlet.2006.10.052

upstream raw materials:

N,N-dimethyl-formamide dimethyl acetal

indolizine

acetic anhydride

acetyl chloride