alpha-D-Galactopyranosiduronic acid, methyl 3,4-O-(1-methylethylidene) -, methyl ester

Base Information

• Chemical Name: alpha-D-Galactopyranosiduronic acid, methyl 3,4-O-(1-methylethylidene) -, methyl ester
• CAS No.: 25253-47-8
• Molecular Formula: C11H18 O7
• Molecular Weight: 262.26
• Mol file: 25253-47-8.mol

Synonyms:Galactopyranosiduronicacid, methyl 3,4-O-isopropylidene-, methyl ester, a-D- (8CI); 4H-1,3-Dioxolo[4,5-c]pyran, a-D-galactopyranosiduronic acidderiv.

Chemical Property of alpha-D-Galactopyranosiduronic acid, methyl 3,4-O-(1-methylethylidene) -, methyl ester

Chemical Property:

• PSA: 83.45000
• LogP: -0.58830

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of alpha-D-Galactopyranosiduronic acid, methyl 3,4-O-(1-methylethylidene) -, methyl ester

There total 5 articles about alpha-D-Galactopyranosiduronic acid, methyl 3,4-O-(1-methylethylidene) -, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2,2-dimethoxy-propane (77-76-9) + methyl (methyl α-D-galacturonopyranoside)uronate (5155-54-4,528584-66-9) → methyl (methyl 3,4-O-isopropylidene-α-D-galactopyranoside)uronate (25253-47-8)

Guidance literature:

With sulfonic acid; In acetone; at 22 ℃; for 4h;

DOI:10.1039/c1ob05587a

Reference yield:

acetone (67-64-1) + methyl (methyl α-D-galacturonopyranoside)uronate (5155-54-4,528584-66-9) → methyl (methyl 3,4-O-isopropylidene-α-D-galactopyranoside)uronate (25253-47-8)

Guidance literature:

With copper(II) sulfate; acetaldehyde;

DOI:10.1039/jr9530002473 DOI:10.1039/jr9470001340

Reference yield:

D-galacturonic acid (685-73-4,25249-06-3,25990-10-7,36562-70-6,36655-86-4) → methyl (methyl 3,4-O-isopropylidene-α-D-galactopyranoside)uronate (25253-47-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen chloride

2: copper (II)-sulfate; acetaldehyde

With hydrogenchloride; copper(II) sulfate; acetaldehyde;

DOI:10.1039/jr9470001340

upstream raw materials:

acetone

methyl (methyl α-D-galacturonopyranoside)uronate

D-galacturonic acid

2,2-dimethoxy-propane

Downstream raw materials:

methyl (2,3-di-O-acetyl-3-C-(benzyloxymethyl)-β-D-erythrofuranosyl)-(1->2) (methyl 3,4-O-isopropylidene-α-D-galactopyranosid)uronate

O¹,O²-dimethyl-α-D-galactopyranuronic acid amide

methyl (2,3-O-(S)-benzylidene-3-C-chloroacetoxymethyl-β-D-erythrofuranosyl)-(1->2)-(methyl 3,4-O-isopropylidene-α-D-galactopyranoside)uronate

methyl (2,3-O-(S)-benzylidene-3-C-hydroxymethyl-β-D-erythrofuranosyl)-(1->2)-(methyl 3,4-O-isopropylidene-α-D-galactopyranoside)uronate