C₃₅H₃₅ClO₉S₃

Base Information

• Chemical Name: C₃₅H₃₅ClO₉S₃
• CAS No.: 173776-70-0
• Molecular Formula: C₃₅H₃₅ClO₉S₃
• Molecular Weight: 731.308
• Mol file: 173776-70-0.mol

Synonyms:C₃₅H₃₅ClO₉S₃

Chemical Property of C₃₅H₃₅ClO₉S₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₃₅ClO₉S₃

There total 11 articles about C₃₅H₃₅ClO₉S₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-1-(4-methanesulfonylphenyl)ethanone (50413-24-6) → C35H35ClO9S3 (173776-70-0)

Guidance literature:

Multi-step reaction with 5 steps

1: 63.3 percent / K₂CO₃, KI / tetrahydrofuran / 6 h / Ambient temperature

2: 73 percent / K₂CO₃, KI / tetrahydrofuran

3: 50 percent / titanium(III) chloride, zinc dust / 1,2-dimethoxy-ethane / 1 h / Heating

4: DIBAL / tetrahydrofuran / 1.) -78 deg C, 15 min, 2.) RT, overnight

5: pyridine / Ambient temperature

With pyridine; titanium(III) chloride; diisobutylaluminium hydride; potassium carbonate; potassium iodide; zinc; In tetrahydrofuran; 1,2-dimethoxyethane;

DOI:10.1021/jm950664x

Reference yield:

4-(Methylthio)acetophenone (1778-09-2) → C35H35ClO9S3 (173776-70-0)

Guidance literature:

Multi-step reaction with 7 steps

1: 91 percent / mCPBA / CH₂Cl₂ / Ambient temperature

2: 15.7 g / HCl, bromine / acetic acid

3: 63.3 percent / K₂CO₃, KI / tetrahydrofuran / 6 h / Ambient temperature

4: 73 percent / K₂CO₃, KI / tetrahydrofuran

5: 50 percent / titanium(III) chloride, zinc dust / 1,2-dimethoxy-ethane / 1 h / Heating

6: DIBAL / tetrahydrofuran / 1.) -78 deg C, 15 min, 2.) RT, overnight

7: pyridine / Ambient temperature

With pyridine; hydrogenchloride; bromine; titanium(III) chloride; diisobutylaluminium hydride; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; potassium iodide; zinc; In tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; acetic acid;

DOI:10.1021/jm950664x

Reference yield:

4-(methanesulfonyl)acetophenone (10297-73-1) → C35H35ClO9S3 (173776-70-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 15.7 g / HCl, bromine / acetic acid

2: 63.3 percent / K₂CO₃, KI / tetrahydrofuran / 6 h / Ambient temperature

3: 73 percent / K₂CO₃, KI / tetrahydrofuran

4: 50 percent / titanium(III) chloride, zinc dust / 1,2-dimethoxy-ethane / 1 h / Heating

5: DIBAL / tetrahydrofuran / 1.) -78 deg C, 15 min, 2.) RT, overnight

6: pyridine / Ambient temperature

With pyridine; hydrogenchloride; bromine; titanium(III) chloride; diisobutylaluminium hydride; potassium carbonate; potassium iodide; zinc; In tetrahydrofuran; 1,2-dimethoxyethane; acetic acid;

DOI:10.1021/jm950664x

upstream raw materials:

2-bromo-1-(4-methanesulfonylphenyl)ethanone

4-(Methylthio)acetophenone

4-(methanesulfonyl)acetophenone

p-cyanophenyl methyl sulfide

Downstream raw materials:

5-(3-chloro-4-methoxyphenyl)-6-[4-(methylsulfonyl)phenyl]spiro[2.4]hept-5-ene