Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

4'-(Methylthio)acetophenone

Base Information Edit
  • Chemical Name:4'-(Methylthio)acetophenone
  • CAS No.:1778-09-2
  • Molecular Formula:C9H10OS
  • Molecular Weight:166.244
  • Hs Code.:29309099
  • European Community (EC) Number:217-213-1
  • NSC Number:403927
  • UNII:FN9JM37X2P
  • DSSTox Substance ID:DTXSID3075129
  • Nikkaji Number:J203.176K
  • Wikidata:Q72491333
  • Mol file:1778-09-2.mol
4'-(Methylthio)acetophenone

Synonyms:1778-09-2;4'-(Methylthio)acetophenone;1-(4-(Methylthio)phenyl)ethanone;4'-methylthioacetophenone;4-(Methylthio)acetophenone;1-(4-methylsulfanylphenyl)ethanone;4'-(Methylmercapto)acetophenone;1-[4-(Methylsulfanyl)phenyl]ethanone;1-(4-(Methylthio)phenyl)ethan-1-one;Ethanone, 1-[4-(methylthio)phenyl]-;1-[4-(methylsulfanyl)phenyl]ethan-1-one;1-[4-(methylthio)phenyl]ethanone;p-(methylthio)acetophenone;C9H10OS;1-[4-(Methylthio)phenyl]ethan-1-one;4-Acetylphenyl methyl sulfide;4-(Methylsulfenyl)acetophenone;1-Acetyl-4-(methylthio)benzene;4-(Acetyl)thioanisole;EINECS 217-213-1;NSC-403927;Ethanone, 1-(4-(methylthio)phenyl)-;4-acetylthioanisole;NSC403927;4-methylthioacetophenone;1-(p-tolyl)ethanethione;4-methylmercaptoacetophenone;FN9JM37X2P;p-Acetylphenyl methyl sulfide;4'-(methylthio) acetophenone;p-(Methylmercapto)acetophenone;SCHEMBL195321;4-CH3S-C6H4-COCH3;DTXSID3075129;1-(4-methylthiophenyl)ethan-1-one;BCP20233;4'-(Methylthio)acetophenone, 97%;BBL009965;MFCD00039835;STK801365;1-(4-methylsulfanyl-phenyl)-ethanone;AKOS000123187;AM10561;CS-W017854;FS-1766;NSC 403927;1-(4-Methylsulphanylphenyl)-1-ethanone;1-[4-(Methylsulfanyl)phenyl]ethanone #;NCGC00342931-01;A3943;FT-0616801;M1672;EN300-11162;F14884;AB01334813-02;AB-131/40227350;J-802122;W-107825;Z57036277

Suppliers and Price of 4'-(Methylthio)acetophenone
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 4''-(Methylthio)acetophenone
  • 1g
  • $ 50.00
  • TCI Chemical
  • 4'-(Methylthio)acetophenone >98.0%(GC)
  • 5g
  • $ 65.00
  • TCI Chemical
  • 4'-(Methylthio)acetophenone >98.0%(GC)
  • 25g
  • $ 193.00
  • SynQuest Laboratories
  • 4'-(Methylthio)acetophenone
  • 100 g
  • $ 240.00
  • SynQuest Laboratories
  • 4'-(Methylthio)acetophenone
  • 25 g
  • $ 120.00
  • SynQuest Laboratories
  • 4'-(Methylthio)acetophenone
  • 5 g
  • $ 40.00
  • Sigma-Aldrich
  • 4′-(Methylthio)acetophenone 97%
  • 1g
  • $ 59.50
  • Oakwood
  • 4-(Methylthio)acetophenone 98%
  • 250g
  • $ 295.00
  • Oakwood
  • 4-(Methylthio)acetophenone 98%
  • 5g
  • $ 16.00
  • Oakwood
  • 4-(Methylthio)acetophenone 98%
  • 10g
  • $ 25.00
Total 96 raw suppliers
Chemical Property of 4'-(Methylthio)acetophenone Edit
Chemical Property:
  • Appearance/Colour:White to light yellow crystal powder 
  • Melting Point:80-82 °C(lit.) 
  • Refractive Index:1.5600 (estimate) 
  • Boiling Point:282.5 °C at 760 mmHg 
  • Flash Point:140.7 °C 
  • PSA:42.37000 
  • Density:1.1 g/cm3 
  • LogP:2.61110 
  • Storage Temp.:Sealed in dry,Room Temperature 
  • Solubility.:Chloroform, Methanol 
  • XLogP3:2.3
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:2
  • Exact Mass:166.04523611
  • Heavy Atom Count:11
  • Complexity:137
Purity/Quality:

99.9% *data from raw suppliers

4''-(Methylthio)acetophenone *data from reagent suppliers

Safty Information:
  • Pictogram(s): IrritantXi 
  • Hazard Codes:Xi 
  • Statements: 36/37/38 
  • Safety Statements: 26-36 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:CC(=O)C1=CC=C(C=C1)SC
  • Uses 4′-(Methylthio)acetophenone may be used for the synthesis of Vioxx (Rofecoxib), an non-steroidal anti-inflammatory drug (NSAID). It may be used in the synthesis of (E)-1-[4-(methylsulfanyl)phenyl]-3-phenylprop-2-en-1-one.
Technology Process of 4'-(Methylthio)acetophenone

There total 52 articles about 4'-(Methylthio)acetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With tert.-butylhydroperoxide; C21H19N5Pd(2+)*2BF4(1-); In decane; acetonitrile; at 45 ℃; for 4h;
DOI:10.1021/acscatal.0c02729
Guidance literature:
With hydrogen; In 1,4-dioxane; at 100 ℃; for 1h; under 760.051 Torr; chemoselective reaction;
DOI:10.1002/anie.201403425
Guidance literature:
With caesium carbonate; In dimethyl sulfoxide; at 80 ℃; for 1h;
DOI:10.1039/c8ob01758a
Post RFQ for Price