C₃₄H₅₈O₅SSi₂

Base Information

• Chemical Name: C₃₄H₅₈O₅SSi₂
• CAS No.: 157220-44-5
• Molecular Formula: C₃₄H₅₈O₅SSi₂
• Molecular Weight: 635.069
• Mol file: 157220-44-5.mol

Synonyms:C₃₄H₅₈O₅SSi₂

Chemical Property of C₃₄H₅₈O₅SSi₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₄H₅₈O₅SSi₂

There total 14 articles about C₃₄H₅₈O₅SSi₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C34H58O3SSi2 (179945-14-3) → C34H58O5SSi2 (157220-44-5)

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 23 ℃; for 1h;

DOI:10.1021/jo9606113

Reference yield:

(2S,3S,4S,5S)-7-Benzyloxy-2,4-dimethyl-5-triethylsilanyloxy-heptane-1,3-diol (157220-42-3) → C34H58O5SSi2 (157220-44-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / trubutylphosphine / dimethylformamide / 4 h / 23 °C

2: 100 percent / imidazole / dimethylformamide / 2.5 h / 23 °C

3: 100 percent / NaHCO₃, m-chloroperoxybenzoic acid / CH₂Cl₂ / 1 h / 23 °C

With 1H-imidazole; tributylphosphine; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo9606113

Reference yield:

(2R,3R,4S,5S)-7-Benzyloxy-2,4-dimethyl-1-phenylsulfanyl-5-triethylsilanyloxy-heptan-3-ol (157220-43-4) → C34H58O5SSi2 (157220-44-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / imidazole / dimethylformamide / 2.5 h / 23 °C

2: 100 percent / NaHCO₃, m-chloroperoxybenzoic acid / CH₂Cl₂ / 1 h / 23 °C

With 1H-imidazole; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo9606113

upstream raw materials:

C₃₄H₅₈O₃SSi₂

triethylsilyl chloride

3-Benzyloxypropanal

(E)-(4S,5S)-7-Benzyloxy-4-methyl-5-triethylsilanyloxy-hept-2-en-1-ol

Downstream raw materials:

(2R,3R)-2-[(1S,2R,5S,6S,7R,8S)-10-Benzenesulfonyl-2-(3,4-dimethoxy-benzyloxymethoxy)-1,5,7-trimethyl-6,8-bis-triethylsilanyloxy-decyl]-5-methoxy-3-methyl-tetrahydro-furan

Refernces

• 1、 Kigoshi, Hideo,Ojika, Makoto,Suenaga, Kiyotake,Mutou, Tsuyoshi,Hirano, Junko,Sakakura, Akira,Ogawa, Takeshi,Nisiwaki, Masanori,Yamada, Kiyoyuki. "Synthetic studies on aplyronine A, a potent antitumor substance of marine origin: Stereocontrolled synthesis of the C21-C34 segment". . p. 1247 - 1250. Retrieved 2007/10/02.