(E)-4-(1-phenylethylidene)-3-isochromanone

Base Information

• Chemical Name: (E)-4-(1-phenylethylidene)-3-isochromanone
• CAS No.: 1338726-11-6
• Molecular Formula: C₁₇H₁₄O₂
• Molecular Weight: 250.297
• Mol file: 1338726-11-6.mol

Synonyms:(E)-4-(1-phenylethylidene)-3-isochromanone

Chemical Property of (E)-4-(1-phenylethylidene)-3-isochromanone

Chemical Property:

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Technology Process of (E)-4-(1-phenylethylidene)-3-isochromanone

There total 1 articles about (E)-4-(1-phenylethylidene)-3-isochromanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

carbon dioxide (124-38-9,18923-20-1) + [2-(2-phenylethynyl)phenyl]methanol (13141-40-7) + dimethyl zinc(II) (544-97-8) → (E)-4-(1-phenylethylidene)-3-isochromanone (1338726-11-6)

Guidance literature:

carbon dioxide; [2-(2-phenylethynyl)phenyl]methanol; dimethyl zinc(II); With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; cesium fluoride; In toluene; acetonitrile; at 50 ℃; for 6h; Inert atmosphere;

With hydrogenchloride; In water; stereoselective reaction; Inert atmosphere;

DOI:10.1021/ol202520x

upstream raw materials:

carbon dioxide

[2-(2-phenylethynyl)phenyl]methanol

dimethyl zinc(II)