(1H-benzimidazol-2-ylsulfanyl)acetic acid (2-hydroxy-3-methoxybenzylidene)hydrazide

Base Information

• Chemical Name: (1H-benzimidazol-2-ylsulfanyl)acetic acid (2-hydroxy-3-methoxybenzylidene)hydrazide
• CAS No.: 132371-34-7
• Molecular Formula: C₁₇H₁₆N₄O₃S
• Molecular Weight: 356.405
• Mol file: 132371-34-7.mol

Synonyms:(1H-benzimidazol-2-ylsulfanyl)acetic acid (2-hydroxy-3-methoxybenzylidene)hydrazide

Chemical Property of (1H-benzimidazol-2-ylsulfanyl)acetic acid (2-hydroxy-3-methoxybenzylidene)hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1H-benzimidazol-2-ylsulfanyl)acetic acid (2-hydroxy-3-methoxybenzylidene)hydrazide

There total 4 articles about (1H-benzimidazol-2-ylsulfanyl)acetic acid (2-hydroxy-3-methoxybenzylidene)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-((1H-benzo[d]imidazole-2-yl)thio)acetohydrazide (30065-27-1) + 3-methoxy-2-hydroxybenzaldehyde (148-53-8) → (1H-benzimidazol-2-ylsulfanyl)acetic acid (2-hydroxy-3-methoxybenzylidene)hydrazide (132371-34-7)

Guidance literature:

With acetic acid; In ethanol; for 4h; Heating;

Reference yield:

ethyl 2-(1H-benzo[d]imidazol-2-ylthio)acetate (5429-62-9) → (1H-benzimidazol-2-ylsulfanyl)acetic acid (2-hydroxy-3-methoxybenzylidene)hydrazide (132371-34-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / 98percent aq. hydrazine hydrate / ethanol / 5 h / Heating

2: 90 percent / acetic acid / ethanol / 4 h / Heating

With hydrazine hydrate; acetic acid; In ethanol;

Reference yield:

Benzimidazol-2-thiol (134469-07-1) → (1H-benzimidazol-2-ylsulfanyl)acetic acid (2-hydroxy-3-methoxybenzylidene)hydrazide (132371-34-7)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / acetone / 3 h / Heating

2: 92 percent / 98percent aq. hydrazine hydrate / ethanol / 5 h / Heating

3: 90 percent / acetic acid / ethanol / 4 h / Heating

With potassium carbonate; hydrazine hydrate; acetic acid; In ethanol; acetone;

upstream raw materials:

2-((1H-benzo[d]imidazole-2-yl)thio)acetohydrazide

3-methoxy-2-hydroxybenzaldehyde

ethyl 2-(1H-benzo[d]imidazol-2-ylthio)acetate

Benzimidazol-2-thiol

Downstream raw materials:

C₁₉H₁₈N₄O₄S₂