methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate

Base Information

Chemical Name:methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate
CAS No.:1401462-40-5
Molecular Formula:C₁₉H₂₁N₅O₄S
Molecular Weight:415.473
Hs Code.:

Synonyms:methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate

Suppliers and Price of methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate

There total 3 articles about methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 198959-37-4
pyrrolidine-3-carboxylic acid methyl ester hydrochloride

: 1401461-83-3
(5-chlorothiazolo[5,4-d]pyrimidin-7-yl)-(3,4-dimethoxyphenyl)amine

: 1401462-40-5
methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; XPhos; In 1,4-dioxane; at 95 ℃; for 24h; Inert atmosphere;
DOI:10.1021/jm301367c

Reference yield:

: 13479-88-4
5,7-dichloro-[1,3]thiazolo[5,4-d]pyrimidine

: 1401462-40-5
methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 24 h / 20 °C

2: caesium carbonate; XPhos / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 20 - 95 °C / Inert atmosphere

With caesium carbonate; N-ethyl-N,N-diisopropylamine; XPhos; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; dimethyl sulfoxide;

Reference yield:

: 6315-89-5
3,4-dimethoxyaniline

: 1401462-40-5
methyl 1-(7-(3,4-dimethoxyphenylamino)thiazolo[5,4-d]pyrimidin-5-yl)pyrrolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / dimethyl sulfoxide / 24 h / 20 °C

2: caesium carbonate; XPhos / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / 1,4-dioxane / 20 - 95 °C / Inert atmosphere

With caesium carbonate; N-ethyl-N,N-diisopropylamine; XPhos; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; dimethyl sulfoxide;