adamantan-1-yl(phenyl)methanol

Base Information

• Chemical Name: adamantan-1-yl(phenyl)methanol
• CAS No.: 786-08-3
• Molecular Formula: C₁₇H₂₂O
• Molecular Weight: 242.361
• Mol file: 786-08-3.mol

Synonyms:adamantan-1-yl(phenyl)methanol

Chemical Property of adamantan-1-yl(phenyl)methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of adamantan-1-yl(phenyl)methanol

There total 19 articles about adamantan-1-yl(phenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1-benzoyladamantane (31919-47-8) → adamantan-1-yl(phenyl)methanol (786-08-3)

Guidance literature:

With LiAlH; In diethyl ether; at 20 ℃; for 2h;

DOI:10.1021/ja993517n

Reference yield: 70.0%

adamantylmagnesium bromide (57680-77-0) + benzaldehyde (100-52-7) → adamantan-1-yl(phenyl)methanol (786-08-3)

Guidance literature:

In diethyl ether; at 0 - 20 ℃;

DOI:10.1021/jo00142a023

Reference yield: 50.0%

(1-adamantyl)diazophenylmethane (180515-91-7) → adamantan-1-yl(phenyl)methanol (786-08-3) + 1-benzoyladamantane (31919-47-8) + N,N'-Bis-[1-adamantan-1-yl-1-phenyl-meth-(Z)-ylidene]-hydrazine

Guidance literature:

(1-adamantyl)diazophenylmethane; In benzene; at 20 ℃; for 1h; Irradiation;

With silica gel;

DOI:10.1021/jacs.0c02221

upstream raw materials:

1-benzoyladamantane

1-Adamantyl bromide

benzaldehyde

adamantylmagnesium bromide

Downstream raw materials:

[(1'-adamantyl)phenylmethoxy]trimethylsilane

4-(1-adamantylmethyl)aniline

(4-Adamantan-1-ylmethyl-phenyl)-carbamic acid ethyl ester

α-(1-adamantyl)-o-nitrotoluene

Refernces

• 1、 Nagaki, Aiichiro,Yamashita, Hiroki,Hirose, Katsuyuki,Tsuchihashi, Yuta,Yoshida, Jun-ichi. "Alkyllithium Compounds Bearing Electrophilic Functional Groups: A Flash Chemistry Approach". supporting information. p. 4027 - 4030. Retrieved 2019/02/24.
• 2、 Shailaja,Kaanumalle, Lakshmi S.,Sivasubramanian, Karthikeyan,Natarajan, Arunkumar,Ponchot, Keith J.,Pradhan, Ajit,Ramamurthy. "Asymmetric induction during electron transfer mediated photoreduction of carbonyl compounds: Role of zeolites". . p. 1561 - 1571. Retrieved 2008/02/03.