4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline

Base Information

• Chemical Name: 4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline
• CAS No.: 1219091-29-8
• Molecular Formula: C₂₄H₂₁NO₂S
• Molecular Weight: 387.502
• Mol file: 1219091-29-8.mol

Synonyms:4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline

Chemical Property of 4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline

There total 11 articles about 4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

tributyl(thien-2-yl)stannane (54663-78-4) + 4-bromo-N,N-bis-(4-methoxyphenyl)aniline (194416-45-0) → 4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline (1219091-29-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 115 ℃; Inert atmosphere;

DOI:10.1002/anie.201905624

Reference yield: 85.0%

2-thiopheneboronic acid pinacol ester (193978-23-3) + 4-bromo-N,N-bis-(4-methoxyphenyl)aniline (194416-45-0) → 4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline (1219091-29-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In toluene; at 40 ℃; for 2h; Inert atmosphere;

Reference yield: 85.0%

→ 4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline (1219091-29-8)

Guidance literature:

upstream raw materials:

tributyl(thien-2-yl)stannane

4-bromo-N,N-bis-(4-methoxyphenyl)aniline

para-iodoanisole

aniline

Downstream raw materials:

p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde

5′-(4-(bis(4-methoxyphenyl)amino)phenyl)-[2,2′-bithiophene]-5-carbaldehyde