p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde

Base Information

• Chemical Name: p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde
• CAS No.: 1199940-64-1
• Molecular Formula: C₃₁H₂₅NO₃S
• Molecular Weight: 491.61
• Mol file: 1199940-64-1.mol

Synonyms:p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde

Chemical Property of p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde

There total 2 articles about p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline (1219091-29-8) + 4-bromo-benzaldehyde (1122-91-4) → p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde (1199940-64-1)

Guidance literature:

4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; Inert atmosphere;

With tributyltin chloride; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;

4-bromo-benzaldehyde; With bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 90 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tet.2009.09.036

Reference yield: 68.0%

→ p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde (1199940-64-1)

Guidance literature:

Reference yield: 61.0%

p-(5-(p-(di(4-methoxyphenyl)amino)phenyl)thiophen-2-yl)benzaldehyde (1199940-64-1) + cyanoacetic acid (372-09-8) → (E)-2-cyano-3-(p-(5'-(p-(di(4-methoxy)phenylamino))-phenyl)-thiophen-2'-yl)phenylacrylic acid (1199940-50-5)

Guidance literature:

With ammonium acetate; acetic acid; at 90 - 100 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.tet.2009.09.036

upstream raw materials:

4-methoxy-N-(4-methoxyphenyl)-N-(4-(thiophen-2-yl)phenyl)aniline

4-bromo-benzaldehyde

Downstream raw materials:

(E)-2-cyano-3-(p-(5'-(p-(di(4-methoxy)phenylamino))-phenyl)-thiophen-2'-yl)phenylacrylic acid