4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]toluene

Base Information

• Chemical Name: 4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]toluene
• CAS No.: 1068439-06-4
• Molecular Formula: C₁₂H₁₇O₂PS₃
• Molecular Weight: 320.438
• Mol file: 1068439-06-4.mol

Synonyms:4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]toluene

Chemical Property of 4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]toluene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]toluene

There total 5 articles about 4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]toluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

bis-(5,5-dimethyl-2-thiono-1,3,2-dioxaphosphorinan-2-yl)disulfide (4073-59-0) + para-thiocresol (106-45-6) → 4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]toluene (1068439-06-4)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; at 0 ℃; for 0.0833333h; Solvent;

DOI:10.1039/c5ra04173b

Reference yield: 95.0%

(5,5-dimethyl-2-thiono-1,3,2-dioxophosphorinanyl) sulfenyl bromide (934751-37-8) + para-thiocresol (106-45-6) → 4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]toluene (1068439-06-4)

Guidance literature:

In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1055/s-0028-1088161

Reference yield: 91.0%

5,5-dimethyl-2-thiolo-2-thiono-1,3,2-dioxaphosphorinane (697-45-0) + para-thiocresol (106-45-6) → 4-[(5,5-dimethyl-2-thioxo-1,3,2-dioxaphosphorinan-2-yl)disulfanyl]toluene (1068439-06-4)

Guidance literature:

5,5-dimethyl-2-thiolo-2-thiono-1,3,2-dioxaphosphorinane; With bromine; In dichloromethane; at -30 ℃; for 0.25h; Inert atmosphere;

para-thiocresol; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1055/s-2008-1067118

upstream raw materials:

5,5-dimethyl-2-thiolo-2-thiono-1,3,2-dioxaphosphorinane

para-thiocresol

bis-(5,5-dimethyl-2-thiono-1,3,2-dioxaphosphorinan-2-yl)disulfide

(5,5-dimethyl-2-thiono-1,3,2-dioxophosphorinanyl) sulfenyl bromide

Downstream raw materials:

1-(4-methylphenyldisulfanyl)-4-methoxybenzene

4-methylphenyl 4-hydroxyphenyl disulfide

4-(phenyldisulfanyl)toluene

4-nitrophenyl p-tolyl disulfide