N-[4-(4-NITRO-2-SULFAMOYL-BENZENESULFONYL)-PHENYL]-ACETAMIDE

Base Information

• Chemical Name: N-[4-(4-NITRO-2-SULFAMOYL-BENZENESULFONYL)-PHENYL]-ACETAMIDE
• CAS No.: 25006-65-9
• Molecular Formula: C14H13N3O7S2
• Molecular Weight: 399.405
• Hs Code.: 2935009090
• Mol file: 25006-65-9.mol

Synonyms:Acetanilide,4'-[(4-nitro-2-sulfamoylphenyl)sulfonyl]- (8CI);N-[4-(4-Nitro-2-sulfamoylphenyl)sulfonylphenyl]acetamide;

Chemical Property of N-[4-(4-NITRO-2-SULFAMOYL-BENZENESULFONYL)-PHENYL]-ACETAMIDE

Chemical Property:

• Refractive Index: 1.65
• PSA: 185.98000
• Density: 1.587 g/cm³
• LogP: 4.49150

Purity/Quality:

97% ^*data from raw suppliers

N-[4-(4-NITRO-2-SULFAMOYL-BENZENESULFONYL)-PHENYL]-ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-[4-(4-NITRO-2-SULFAMOYL-BENZENESULFONYL)-PHENYL]-ACETAMIDE

There total 5 articles about N-[4-(4-NITRO-2-SULFAMOYL-BENZENESULFONYL)-PHENYL]-ACETAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-acetylamino-phenylsulfanyl)-5-nitro-benzenesulfonic acid amide (861062-46-6) → 2-(N-acetyl-sulfanilyl)-5-nitro-benzenesulfonic acid amide (25006-65-9)

Guidance literature:

With dihydrogen peroxide;

DOI:10.1021/jo01148a027

Reference yield:

S-[4-(acetylamino)phenyl] ethanethioate (946-94-1) → 2-(N-acetyl-sulfanilyl)-5-nitro-benzenesulfonic acid amide (25006-65-9)

Guidance literature:

Multi-step reaction with 3 steps

1: aq.-ethanolic NaOH

3: aqueous H₂O₂

With sodium hydroxide; dihydrogen peroxide;

DOI:10.1021/jo01148a027

Reference yield:

4-chlorobenzonitrile (100-00-5) → 2-(N-acetyl-sulfanilyl)-5-nitro-benzenesulfonic acid amide (25006-65-9)

Guidance literature:

Multi-step reaction with 4 steps

1: aqueous Na₂S / und anschliessend mit Acetanhydrid

2: aq.-ethanolic NaOH

4: aqueous H₂O₂

With sodium sulfide; sodium hydroxide; dihydrogen peroxide;

DOI:10.1021/jo01148a027

upstream raw materials:

2-(4-acetylamino-phenylsulfanyl)-5-nitro-benzenesulfonic acid amide

4-acetamidobenzenesulfinic acid

S-[4-(acetylamino)phenyl] ethanethioate

4-chlorobenzonitrile

Downstream raw materials:

5-acetylamino-2-(N-acetyl-sulfanilyl)-benzenesulfonic acid amide

acetyl-(5-amino-2-sulfanilyl-benzenesulfonyl)-amine

5-amino-2-sulfanilyl-benzenesulfonic acid amide

5-nitro-2-sulfanilyl-benzenesulfonic acid amide