N-hydroxy-3-{7-oxo-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl}benzamidine

Base Information

Chemical Name:N-hydroxy-3-{7-oxo-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl}benzamidine
CAS No.:503612-97-3
Molecular Formula:C₂₅H₁₉F₃N₆O₃
Molecular Weight:508.459
Hs Code.:

Synonyms:N-hydroxy-3-{7-oxo-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl}benzamidine

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Chemical Property of N-hydroxy-3-{7-oxo-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl}benzamidine

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Technology Process of N-hydroxy-3-{7-oxo-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl}benzamidine

There total 3 articles about N-hydroxy-3-{7-oxo-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl}benzamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₅H₁₆F₃N₅O₂

: 503612-97-3
N-hydroxy-3-{7-oxo-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl}benzamidine

Guidance literature:: With hydroxylamine hydrochloride; triethylamine; In methanol; at 20 ℃; for 48h;

Reference yield:

: 142-08-5
2-hydroxypyridin

: 503612-97-3
N-hydroxy-3-{7-oxo-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl}benzamidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; copper(l) iodide / 18 h / Reflux

2: triethylamine; hydroxylamine hydrochloride / methanol / 48 h / 20 °C

With copper(l) iodide; hydroxylamine hydrochloride; potassium carbonate; triethylamine; In methanol;

Reference yield:

: 385425-17-2
3-[6-(4-iodophenyl)-7-oxo-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl]benzonitrile

: 503612-97-3
N-hydroxy-3-{7-oxo-6-[4-(2-oxo-2H-pyridin-1-yl)phenyl]-3-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridin-1-yl}benzamidine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; copper(l) iodide / 18 h / Reflux

2: triethylamine; hydroxylamine hydrochloride / methanol / 48 h / 20 °C

With copper(l) iodide; hydroxylamine hydrochloride; potassium carbonate; triethylamine; In methanol;