rac-N-(2-iodo-4,6-dimethylphenyl)-N-(3-methylbut-2-enyl)acetamide

Base Information

• Chemical Name: rac-N-(2-iodo-4,6-dimethylphenyl)-N-(3-methylbut-2-enyl)acetamide
• CAS No.: 720714-32-9
• Molecular Formula: C₁₅H₂₀INO
• Molecular Weight: 357.234
• Mol file: 720714-32-9.mol

Synonyms:rac-N-(2-iodo-4,6-dimethylphenyl)-N-(3-methylbut-2-enyl)acetamide

Chemical Property of rac-N-(2-iodo-4,6-dimethylphenyl)-N-(3-methylbut-2-enyl)acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-N-(2-iodo-4,6-dimethylphenyl)-N-(3-methylbut-2-enyl)acetamide

There total 2 articles about rac-N-(2-iodo-4,6-dimethylphenyl)-N-(3-methylbut-2-enyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

N-(2-iodo-4,6-dimethylphenyl) acetamide (208659-17-0) + prenyl bromide (870-63-3) → rac-N-(2-iodo-4,6-dimethylphenyl)-N-(3-methylbut-2-enyl)acetamide (720714-32-9)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1016/j.tet.2004.02.064

Reference yield:

2-iodo-4,6-dimethylaniline (4102-54-9) → rac-N-(2-iodo-4,6-dimethylphenyl)-N-(3-methylbut-2-enyl)acetamide (720714-32-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / triethylamine / CH₂Cl₂ / 0 - 20 °C

2: 84 percent / NaH / tetrahydrofuran / 0 - 20 °C

With sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1016/j.tet.2004.02.064

upstream raw materials:

N-(2-iodo-4,6-dimethylphenyl) acetamide

prenyl bromide

2-iodo-4,6-dimethylaniline