2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester

Base Information

Chemical Name:2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester
CAS No.:189340-02-1
Molecular Formula:C₂₅H₃₀ClNO₈S
Molecular Weight:540.034
Hs Code.:

Synonyms:2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester

Suppliers and Price of 2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester

There total 7 articles about 2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 123855-51-6
tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate

: 189339-99-9
2-chlorobenzenesulfonic acid 3-hydroxy-5-carbomethoxyphenyl ester

: 1972-28-7,218603-74-8
diethylazodicarboxylate

: 189340-02-1
2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; hexane;

Reference yield:

: 161975-39-9
tert-butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate

: 189339-99-9
2-chlorobenzenesulfonic acid 3-hydroxy-5-carbomethoxyphenyl ester

: 189340-02-1
2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester

Guidance literature:: 2-chlorobenzenesulfonic acid 3-hydroxy-5-carbomethoxyphenyl ester; With sodium hydride; In N,N-dimethyl-formamide;

tert-butyl 4-(((methylsulfonyl)oxy)methyl)piperidine-1-carboxylate; In N,N-dimethyl-formamide; at 50 ℃; for 3h;
DOI:10.1016/S0960-894X(99)00617-4

Reference yield:

: 498-94-2
isonipecotic acid

: 189340-02-1
2-Chlorobenzenesulfonic acid 3-[[1-N-(tert-butoxycarbonyl)piperidin-4-yl]methoxy]-5-carbomethoxyphenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: 91 percent / NaHCO₃ / dioxane; H₂O / 24 h

2.1: 84 percent / BH₃*THF / 0 - 25 °C

3.1: 93 percent / Et₃N / CH₂Cl₂

4.1: NaH / dimethylformamide

4.2: dimethylformamide / 3 h / 50 °C

With borane-THF; sodium hydride; sodium hydrogencarbonate; triethylamine; In 1,4-dioxane; dichloromethane; water; N,N-dimethyl-formamide; 1.1: Acylation / 2.1: Reduction / 3.1: Mesylation / 4.1: Metallation / 4.2: Substitution;
DOI:10.1016/S0960-894X(99)00617-4