3',5'-Dibromo-2'-hydroxypropiophenone

Base Information

• Chemical Name: 3',5'-Dibromo-2'-hydroxypropiophenone
• CAS No.: 2887-68-5
• Molecular Formula: C₉H₈Br₂O₂
• Molecular Weight: 307.969
• Mol file: 2887-68-5.mol

Synonyms:Propiophenone,3',5'-dibromo-2'-hydroxy- (6CI,7CI,8CI); 3',5'-Dibromo-2'-hydroxypropiophenone

Chemical Property of 3',5'-Dibromo-2'-hydroxypropiophenone

Chemical Property:

• PSA: 37.30000
• LogP: 3.50990

Purity/Quality:

99% ^*data from raw suppliers

1-(3,5-DIBROMO-2-HYDROXYPHENYL)PROPAN-1-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3',5'-Dibromo-2'-hydroxypropiophenone

There total 8 articles about 3',5'-Dibromo-2'-hydroxypropiophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-Hydroxy-phenyl)-propan-1-on (610-99-1) → 1-(3,5-dibromo-2-hydroxy-phenyl)-propan-1-one (2887-68-5)

Guidance literature:

With bromine; acetic acid;

DOI:10.1039/jr9550000018

Reference yield:

propionic acid-(2,4-dibromo-phenyl ester) (23689-34-1) → 1-(3,5-dibromo-2-hydroxy-phenyl)-propan-1-one (2887-68-5)

Guidance literature:

With aluminium trichloride; at 160 ℃;

Reference yield:

2,4-dibromophenol (615-58-7) → 1-(3,5-dibromo-2-hydroxy-phenyl)-propan-1-one (2887-68-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Py / benzene

2: AlCl₃ / 100 °C

With pyridine; aluminium trichloride; In benzene;

upstream raw materials:

1-(2-Hydroxy-phenyl)-propan-1-on

propionic acid-(2,4-dibromo-phenyl ester)

2,4-dibromophenol

propionic acid anhydride

Downstream raw materials:

1-(3,5-dibromo-2-methoxy-phenyl)-propan-1-one

4,6-Dibrom-2-<1-hydroxy-propyl>-anisol

2,4-Dibromo-6-(1-hydroxy-propyl)-phenol