3-NITRO-4-AMINODIMETHYLAMINOACETANILIDE

Base Information

• Chemical Name: 3-NITRO-4-AMINODIMETHYLAMINOACETANILIDE
• CAS No.: 29124-72-9
• Molecular Formula: C10H13 N3 O3
• Molecular Weight: 223.23
• Mol file: 29124-72-9.mol

Synonyms:Acetanilide,4'-(dimethylamino)-2'-nitro- (6CI,8CI);N-[4-(Dimethylamino)-2-nitrophenyl]acetamide

Chemical Property of 3-NITRO-4-AMINODIMETHYLAMINOACETANILIDE

Chemical Property:

• Vapor Pressure: 4.99E-08mmHg at 25°C
• Refractive Index: 1.63
• Boiling Point: 442.5°C at 760 mmHg
• Flash Point: 221.4°C
• PSA: 81.65000
• Density: 1.295g/cm³
• LogP: 2.79190

Purity/Quality:

98%Min ^*data from raw suppliers

ACETAMIDE, N-[4-(DIMETHYLAMINO)-2-NITROPHENYL]- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-NITRO-4-AMINODIMETHYLAMINOACETANILIDE

There total 1 articles about 3-NITRO-4-AMINODIMETHYLAMINOACETANILIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

N'-acetyl-N,N-dimethyl-1,4-phenylenediamine (7463-28-7) → 4-N,N-dimethylamino-2-nitroacetanilide (29124-72-9)

Guidance literature:

With sulfuric acid; nitric acid; at 0 ℃;

Reference yield:

4-N,N-dimethylamino-2-nitroacetanilide (29124-72-9) → 4-N,N-dimethylamino-N-methyl-2-nitroaniline (16293-15-5)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH / acetone / 0.5 h / Heating

2: potassium hydroxide / ethanol; H₂O / 1 h / Heating

With potassium hydroxide; In ethanol; water; acetone;

Reference yield:

4-N,N-dimethylamino-2-nitroacetanilide (29124-72-9) + methyl iodide (74-88-4) → N-(4-Dimethylamino-2-nitro-phenyl)-N-methyl-acetamide (85020-97-9)

Guidance literature:

With potassium hydroxide; In acetone; for 0.5h; Heating;

upstream raw materials:

N'-acetyl-N,N-dimethyl-1,4-phenylenediamine

Downstream raw materials:

N⁴,N⁴-Dimethyl-2-nitro-1,4-phenylenediamine

acetic acid-(3-chloro-4-dimethylamino-2-nitro-anilide)

acetic acid-(4-dimethylamino-2,5-dinitro-anilide)

N-(4-Dimethylamino-2-nitro-phenyl)-N-methyl-acetamide