4'-Dimethylaminoacetanilide

Base Information

• Chemical Name: 4'-Dimethylaminoacetanilide
• CAS No.: 7463-28-7
• Molecular Formula: C10H14N2O
• Molecular Weight: 178.234
• Hs Code.: 2924299090
• European Community (EC) Number: 231-253-7
• NSC Number: 404337
• UNII: 8YSM8TQ5P5
• DSSTox Substance ID: DTXSID20225612
• Nikkaji Number: J278.868C
• Wikidata: Q83104656
• Mol file: 7463-28-7.mol

Synonyms:n-[4-(dimethylamino)phenyl]acetamide;4'-Dimethylaminoacetanilide;7463-28-7;4//'-Dimethylaminoacetanilide;EINECS 231-253-7;NSC 404337;NSC-404337;Acetamide, N-(4-(dimethylamino)phenyl)-;Acetamide, N-[4-(dimethylamino)phenyl]-;AI3-17946;N-(4-(Dimethylamino)phenyl)acetamide;4'-(dimethylamino)acetanilide;NSC404337;p-(Dimethylamino)acetanilide;8YSM8TQ5P5;4/'-Dimethylaminoacetanilide;Oprea1_405970;SCHEMBL59093;p-Acetamido-N,N-dimethylaniline;4-acetamido-N,N-dimethylaniline;P-DIMETHYLAMINOACETANILIDE;DTXSID20225612;Acetanilide, 4'-(dimethylamino)-;N,N-Dimethyl-4-(acetylamino)aniline;N-(4-Dimethylamino-phenyl)-acetamide;AKOS002947275;N-acetyl-N',N'-dimethyl-1,4-phenylenediamine;AE-641/00559043;103584-27-6

Chemical Property of 4'-Dimethylaminoacetanilide

Chemical Property:

• Boiling Point: 366.7°Cat760mmHg
• Flash Point: 175.6°C
• PSA: 32.34000
• Density: 1.11g/cm³
• LogP: 1.78400
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 178.110613074
• Heavy Atom Count: 13
• Complexity: 172

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(=O)NC1=CC=C(C=C1)N(C)C

Technology Process of 4'-Dimethylaminoacetanilide

There total 29 articles about 4'-Dimethylaminoacetanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methanol (67-56-1) + N-acetyl-p-phenylenediamine (122-80-5) → N'-acetyl-N,N-dimethyl-1,4-phenylenediamine (7463-28-7)

Guidance literature:

With C₁₅H₂₉IrN₄⁽²⁺⁾*2I^(1-); at 120 ℃; for 17h; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1055/s-0037-1610252

Reference yield: 95.0%

4-dimethylaminoacetophenone oxime (187672-34-0) → N'-acetyl-N,N-dimethyl-1,4-phenylenediamine (7463-28-7)

Guidance literature:

With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; In tetrahydrofuran; ethyl acetate; at 70 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.tetlet.2010.12.090

Reference yield: 87.0%

4-(dimethylamino)benzenediazonium tetrafluoroborate (24564-52-1) + acetonitrile (75-05-8,26809-02-9) + allyl-trimethyl-silane (762-72-1) → N'-acetyl-N,N-dimethyl-1,4-phenylenediamine (7463-28-7) + N,N-dimethyl-4-(2-propen-1-yl)benzenamine (51601-26-4) + N,N-dimethyl-aniline (121-69-7,77733-26-7)

Guidance literature:

Irradiation;

DOI:10.1039/b210243a

upstream raw materials:

acetic anhydride

4-amino-N,N-dimethylaniline

acetic acid

acetamide

Downstream raw materials:

N,N-dimethyl-N'-(4-methoxyphenyl)-1,4-phenylendiamine

acetic acid-(3-chloro-4-dimethylamino-anilide)

4-N,N-dimethylamino-2-nitroacetanilide

N⁴-Acetyl-N¹,N¹-dimethyl-2-nitro-p-phenylendiamin