6-Phenylpyrimidine-4-carboxylic acid

Base Information

Chemical Name:6-Phenylpyrimidine-4-carboxylic acid
CAS No.:28668-32-8
Molecular Formula:C11H8 N2 O2
Molecular Weight:200.197
Hs Code.:2933599090
European Community (EC) Number:624-306-4
ChEMBL ID:CHEMBL3407867
DSSTox Substance ID:DTXSID10503350
Pharos Ligand ID:4N2PR7G2ZXH5
Mol file:28668-32-8.mol

Synonyms:6-Phenylpyrimidine-4-carboxylic acid;28668-32-8;6-Phenyl-4-pyrimidinecarboxylic acid;6-phenyl-pyrimidine-4-carboxylic acid;CHEMBL3407867;4-Pyrimidinecarboxylic acid, 6-phenyl-;MESITYLGLYOXYLICACID;SCHEMBL1578179;DTXSID10503350;KUC107410N;BDBM50072085;MFCD06200701;AKOS015867990;KSC-20-079;SB58207;NS-02034;6-Phenyl-4-pyrimidinecarboxylic acid, 95%;CS-0318214;A1-00171;J-017185;F1967-2300

Suppliers and Price of 6-Phenylpyrimidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-phenylpyrimidine-4-carboxylicAcid
2.5mg
$ 45.00

Sigma-Aldrich
6-Phenyl-4-pyrimidinecarboxylic acid 95%
1g
$ 169.00

Matrix Scientific
6-Phenyl-pyrimidine-4-carboxylicacid 96%
10g
$ 1920.00

Matrix Scientific
6-Phenyl-pyrimidine-4-carboxylicacid 96%
5g
$ 1120.00

Crysdot
6-Phenylpyrimidine-4-carboxylicacid 95+%
1g
$ 313.00

Chemenu
6-phenylpyrimidine-4-carboxylicacid 95%
1g
$ 296.00

Azepine
6-phenylpyrimidine-4-carboxylicacid 95
1 g
$ 390.00

American Custom Chemicals Corporation
6-PHENYL-4-PYRIMIDINECARBOXYLIC ACID 95.00%
1G
$ 788.29

American Custom Chemicals Corporation
6-PHENYL-4-PYRIMIDINECARBOXYLIC ACID 95.00%
100MG
$ 478.80

Alichem
6-Phenylpyrimidine-4-carboxylicacid
1g
$ 614.14

Total 14 raw suppliers

Chemical Property of 6-Phenylpyrimidine-4-carboxylic acid

Chemical Property:

Vapor Pressure:1.54E-08mmHg at 25°C
Melting Point:173-177 °C(lit.)
Refractive Index:1.619
Boiling Point:440.6oC at 760 mmHg
Flash Point:220.3oC
PSA：63.08000
Density:1.302g/cm3
LogP:1.84180
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:200.058577502
Heavy Atom Count:15
Complexity:227

Purity/Quality:

99% ^*data from raw suppliers

6-phenylpyrimidine-4-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-36
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=NC=N2)C(=O)O

Technology Process of 6-Phenylpyrimidine-4-carboxylic acid

There total 9 articles about 6-Phenylpyrimidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 28840-36-0
6-phenylpyrimidine-4-carboxamide

: 28668-32-8
6-phenylpyrimidine-4-carboxylic acid

Guidance literature:: With sulfuric acid; at 100 ℃;
DOI:10.1016/j.bmc.2016.02.046

Reference yield:

: 74647-38-4
6-phenylpyrimidine-4-carboxylic acid methyl ester

: 28668-32-8
6-phenylpyrimidine-4-carboxylic acid

Guidance literature:: 6-phenylpyrimidine-4-carboxylic acid methyl ester; With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 16h;

With water; In dichloromethane;
DOI:10.1021/jm501350y

Reference yield:

: 3438-48-0
4-phenylpyrimidine

: 28668-32-8
6-phenylpyrimidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid; ferrous(II) sulfate heptahydrate; tert.-butylhydroperoxide / 0 - 15 °C

2: sulfuric acid / 100 °C

With tert.-butylhydroperoxide; ferrous(II) sulfate heptahydrate; sulfuric acid;
DOI:10.1016/j.bmc.2016.02.046