2-[N-(carboxymethyl)-4-methylanilino]acetic acid

Base Information Edit

Chemical Name:2-[N-(carboxymethyl)-4-methylanilino]acetic acid
CAS No.:28444-51-1
Molecular Formula:C11H13 N O4
Molecular Weight:223.229
Hs Code.:2922499990
DSSTox Substance ID:DTXSID80405695
Nikkaji Number:J2.131.630J
Wikidata:Q82210381
Mol file:28444-51-1.mol

Synonyms:28444-51-1;2-[N-(carboxymethyl)-4-methylanilino]acetic acid;N,N-DI(CARBOXYMETHYL)-4-METHYLANILIN;N.N-DI(CARBOXYMETHYL)-4-METHYLANILIN;Oprea1_713838;SCHEMBL9974573;DTXSID80405695;AKOS002337877;NCGC00330691-01;[(carboxymethyl)-4-methylanilino]acetic acid;AB01325182-02;AG-690/09285008

Suppliers and Price of 2-[N-(carboxymethyl)-4-methylanilino]acetic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N,N-DI(CARBOXYMETHYL)-4-METHYLANILIN 95.00%
5MG
$ 500.79

Total 1 raw suppliers

Chemical Property of 2-[N-(carboxymethyl)-4-methylanilino]acetic acid Edit

Chemical Property:

PSA：77.84000
LogP:0.97060
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:223.08445790
Heavy Atom Count:16
Complexity:243

Purity/Quality:

97% ^*data from raw suppliers

N,N-DI(CARBOXYMETHYL)-4-METHYLANILIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N(CC(=O)O)CC(=O)O

Technology Process of 2-[N-(carboxymethyl)-4-methylanilino]acetic acid

There total 6 articles about 2-[N-(carboxymethyl)-4-methylanilino]acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 194416-59-6
C₁₅H₂₁NO₄

: 28444-51-1
2,2'-(p-tolylazanediyl)diacetic acid

Guidance literature:: C₁₅H₂₁NO₄; With potassium hydroxide; In ethanol; at 60 ℃; for 1h;

With hydrogenchloride; In water; pH=2;
DOI:10.1248/cpb.c13-00623

Reference yield:

: 106-49-0,12221-03-3
p-toluidine

: 28444-51-1
2,2'-(p-tolylazanediyl)diacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: disodium hydrogenphosphate; sodium iodide / acetonitrile / 12 h / Reflux

2.1: potassium hydroxide / ethanol / 1 h / 60 °C

2.2: pH 2

With disodium hydrogenphosphate; sodium iodide; potassium hydroxide; In ethanol; acetonitrile;
DOI:10.1248/cpb.c13-00623