Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu

Base Information

Chemical Name:Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu
CAS No.:1374459-01-4
Molecular Formula:C₃₃H₄₇N₃O₁₄
Molecular Weight:709.748
Hs Code.:

Synonyms:Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu

Suppliers and Price of Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu

There total 6 articles about Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1374459-00-3
C₂₆H₃₄N₂O₁₃

: 15231-41-1
tert-butyl 3-aminopropanoate

: 1374459-01-4
Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu

Guidance literature:: C₂₆H₃₄N₂O₁₃; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at 0 ℃; for 0.0833333h; Inert atmosphere;

tert-butyl 3-aminopropanoate; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Inert atmosphere;
DOI:10.1016/j.tetlet.2012.03.072

Reference yield:

: 1374458-98-6
2-[3,7-anhydro-2-deoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-1-(benzyloxycarbonyl)hydazone

: 1374459-01-4
Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / toluene / 12 h / 0 °C / Reflux

2.1: trifluoroacetic acid / dichloromethane / 18 h / 20 °C

3.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere

3.2: 3 h / 0 - 20 °C / Inert atmosphere

With 4-methyl-morpholine; potassium carbonate; trifluoroacetic acid; isobutyl chloroformate; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1016/j.tetlet.2012.03.072

Reference yield:

: 1374458-99-7
C₃₀H₄₂N₂O₁₃

: 1374459-01-4
Nα-[3,7-anhydro-1,2-dideoxy-4,5,6,8-tetra-O-acetyl-D-glycero-L-gulo-octitol-1-yl]-(benzyloxycarbonyl)hydrazinoGly-(β)-Ala-OtBu

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / dichloromethane / 18 h / 20 °C

2.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 0.08 h / 0 °C / Inert atmosphere

2.2: 3 h / 0 - 20 °C / Inert atmosphere

With 4-methyl-morpholine; trifluoroacetic acid; isobutyl chloroformate; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tetlet.2012.03.072