methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid

Base Information

• Chemical Name: methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid
• CAS No.: 152342-09-1
• Molecular Formula: C₁₉H₁₆N₂O₂
• Molecular Weight: 304.348
• Mol file: 152342-09-1.mol

Synonyms:methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid

Chemical Property of methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid

There total 3 articles about methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

3-Methoxycarbonylmethyl-2-methyl-1-(2-oxo-2-phenyl-ethyl)-3H-benzoimidazol-1-ium; bromide → methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid (152342-09-1)

Guidance literature:

With sodium methylate; In methanol; Heating;

DOI:10.1007/BF00534470

Reference yield:

methyl 2-(2-methyl-1H-benzimidazol-1-yl)acetate (2033-54-7) → methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid (152342-09-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / acetone / 5 h / Heating

2: 45 percent / sodium methylate / methanol / Heating

With sodium methylate; In methanol; acetone;

DOI:10.1007/BF00534470

Reference yield:

α-bromoacetophenone (70-11-1) → methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid (152342-09-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / acetone / 5 h / Heating

2: 45 percent / sodium methylate / methanol / Heating

With sodium methylate; In methanol; acetone;

DOI:10.1007/BF00534470

upstream raw materials:

methyl 2-(2-methyl-1H-benzimidazol-1-yl)acetate

α-bromoacetophenone