methyl 2-acetate

Base Information

• Chemical Name: methyl 2-acetate
• CAS No.: 2033-54-7
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.229
• Mol file: 2033-54-7.mol

Synonyms:methyl 2-acetate

Chemical Property of methyl 2-acetate

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-acetate

There total 2 articles about methyl 2-acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-Methyl-1H-benzimidazole (615-15-6) + 1-bromoacetone (598-31-2) → methyl 2-acetate (2033-54-7,167266-89-9)

Guidance literature:

With sodium hydride; In tetrahydrofuran; 1.) 3 h; 2.) 1 h, reflux;

DOI:10.1021/ja00282a020

Reference yield: 52.0%

2-Methyl-1H-benzimidazole (615-15-6) + chloroacetone (78-95-5) → methyl 2-acetate (2033-54-7,167266-89-9)

Guidance literature:

With triethylamine; In acetone; for 24h; Reflux;

DOI:10.1002/chir.22591

Reference yield: 92.0%

methyl 2-(2-methyl-1H-benzimidazol-1-yl)acetate (2033-54-7) → 2-(2-methyl-1H-benzimidazol-1-yl)acetohydrazide (97420-40-1)

Guidance literature:

With hydrazine hydrate; In methanol; at 65 ℃; for 16h;

DOI:10.1021/ml400234x

upstream raw materials:

2-Methyl-1H-benzimidazole

1-bromoacetone

chloroacetone

Downstream raw materials:

methyl ester of 2-phenylpyrrolobenzimidazolyl-4-acetic acid

2-(2-methyl-1H-benzimidazol-1-yl)acetohydrazide

N-[2-((5Z,10Z,14Z,19Z)-20-[2-(2,2-Dimethyl-propionylamino)-phenyl]-10,15-bis-{2-[2-(2-methyl-benzoimidazol-1-yl)-acetylamino]-phenyl}-porphyrin-5-yl)-phenyl]-2,2-dimethyl-propionamide

α,α,5,15-bis-α,α,10,20-bis(pivalamidophenyl)porphine