C₁₁H₁₃IN₂O₅

Base Information

• Chemical Name: C₁₁H₁₃IN₂O₅
• CAS No.: 1305317-48-9
• Molecular Formula: C₁₁H₁₃IN₂O₅
• Molecular Weight: 380.139
• Mol file: 1305317-48-9.mol

Synonyms:C₁₁H₁₃IN₂O₅

Chemical Property of C₁₁H₁₃IN₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₁₃IN₂O₅

There total 4 articles about C₁₁H₁₃IN₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-methyl 2-(tert-butoxycarbonylamino)-3-(3-iodo-4-methoxy-5-nitrophenyl)propanoate (1253795-12-8) → C11H13IN2O5 (1305317-48-9)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1002/chem.201000924

Reference yield:

(S)-2-(tert-butoxycarbonylamino)-3-(4-hydroxy-3-iodo-5-nitrophenyl)propanoic acid (1253795-07-1) → C11H13IN2O5 (1305317-48-9)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 48 h / Reflux

2: trifluoroacetic acid / dichloromethane

With potassium carbonate; trifluoroacetic acid; In dichloromethane; acetone;

DOI:10.1021/np200163g

Reference yield:

3-nitro-L-tyrosine (621-44-3) → C11H13IN2O5 (1305317-48-9)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium hydrogencarbonate / water; acetone

2: sodium hydrogencarbonate; N,N,N-trimethylbenzenemethanaminium dichloroiodate / methanol; dichloromethane

3: potassium carbonate / acetone / 48 h / Reflux

4: trifluoroacetic acid / dichloromethane

With sodium hydrogencarbonate; potassium carbonate; N,N,N-trimethylbenzenemethanaminium dichloroiodate; trifluoroacetic acid; In methanol; dichloromethane; water; acetone;

DOI:10.1021/np200163g

upstream raw materials:

(S)-methyl 2-(tert-butoxycarbonylamino)-3-(3-iodo-4-methoxy-5-nitrophenyl)propanoate

(S)-2-(tert-butoxycarbonylamino)-3-(4-hydroxy-3-iodo-5-nitrophenyl)propanoic acid

3-nitro-L-tyrosine

(2S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-3-nitro-phenyl)-propionic acid

Downstream raw materials:

(S)-methyl 2-((S)-2-(tert-butoxycarbonylamino)propanamido)-3-(3-iodo-4-methoxy-5-nitrophenyl)propanoate

C₅₆H₇₉N₇O₁₃

C₃₅H₄₈BIN₄O₁₂