3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-3-(2-hydroxy-ethyl)-pyrrolidine

Base Information

• Chemical Name: 3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-3-(2-hydroxy-ethyl)-pyrrolidine
• CAS No.: 167262-41-1
• Molecular Formula: C₂₂H₂₅Cl₂NO₅
• Molecular Weight: 454.35

Synonyms:3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-3-(2-hydroxy-ethyl)-pyrrolidine

Chemical Property of 3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-3-(2-hydroxy-ethyl)-pyrrolidine

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

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Technology Process of 3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-3-(2-hydroxy-ethyl)-pyrrolidine

There total 7 articles about 3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-3-(2-hydroxy-ethyl)-pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl-2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-acetate (167262-65-9,192069-61-7) → 3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-3-(2-hydroxy-ethyl)-pyrrolidine (167262-41-1)

Guidance literature:

With LiOH; In methanol; dichloromethane;

Reference yield:

3,4,5-Trimethoxybenzoyl chloride (4521-61-3) + 3-(3,4-dichloro-phenyl)-3-(2-hydroxy-ethyl)-pyrrolidine (52423-89-9) → 3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-3-(2-hydroxy-ethyl)-pyrrolidine (167262-41-1)

Guidance literature:

With 4-methyl-morpholine; In methanol; hexane; dichloromethane; ethyl acetate;

Reference yield:

aqueous lithium hydroxide + 1-(3,4,5-trimethoxy-benzoyl)-3-(3,4-dichloro-phenyl)-3-(2-acetoxy-ethyl)-pyrrolidine (178370-78-0) → 3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-3-(2-hydroxy-ethyl)-pyrrolidine (167262-41-1)

Guidance literature:

With hydrogenchloride; In methanol; dichloromethane;

upstream raw materials:

4-methyl-morpholine

3,4,5-Trimethoxybenzoyl chloride

3-(3,4-dichloro-phenyl)-3-(2-hydroxy-ethyl)-pyrrolidine

ethyl-2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-acetate

Downstream raw materials:

2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-ethyl-methanesulfonate

1-(3,4,5-trimethoxy-benzoyl)-3-(3,4-dichloro-phenyl)-3-(2-acetoxy-ethyl)-pyrrolidine

ethyl-2-[3-(3,4-dichloro-phenyl)-1-(3,4,5-trimethoxy-benzoyl)-pyrrolidin-3-yl]-acetate

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