tert-butyl (2S,3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-2-methyl-3-phenylpropionate

Base Information

Chemical Name:tert-butyl (2S,3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-2-methyl-3-phenylpropionate
CAS No.:151214-60-7
Molecular Formula:C₂₉H₃₅NO₂
Molecular Weight:429.602
Hs Code.:

Synonyms:tert-butyl (2S,3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-2-methyl-3-phenylpropionate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl (2S,3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-2-methyl-3-phenylpropionate

Chemical Property:

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Technology Process of tert-butyl (2S,3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-2-methyl-3-phenylpropionate

There total 2 articles about tert-butyl (2S,3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-2-methyl-3-phenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 98831-01-7
(2E)-tert-butyl 2-methyl-3-phenylprop-2-enoate

: lithium benzyl-(R)-1-phenylethylamide

: 151214-60-7
tert-butyl (2S,3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-2-methyl-3-phenylpropionate

Guidance literature:: With 2,6-di-tert-butylphenol; 1.) toluene, -30 deg C, 4 h, 2.) THF, RT;

Reference yield:

: 14990-09-1
tert-butyl cinnamate

: 38235-77-7
(R)-N-benzyl-1-phenylethylamine

: 74-88-4
methyl iodide

: 151214-60-7
tert-butyl (2S,3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-2-methyl-3-phenylpropionate

: 151133-01-6
tert-butyl (2R,3S,αR)-3-(N-benzyl-N-α-methylbenzylamino)-2-methyl-3-phenylpropionate

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) THF, -78 deg C, 2 h, 2.) 15 h;