(2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester

Base Information

Chemical Name:(2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester
CAS No.:85593-71-1
Molecular Formula:C₄₈H₆₂O₄Si₂
Molecular Weight:759.189
Hs Code.:

Synonyms:(2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester

Suppliers and Price of (2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester

There total 9 articles about (2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 144152-65-8
(Diethoxy-phosphanyloxy)-acetic acid ethyl ester

: 85593-70-0
(2E,6Z)-(R)-4,12-Bis-(tert-butyl-diphenyl-silanyloxy)-dodeca-2,6-dienal

: 85593-71-1
(2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester

Guidance literature:: With sodium hydride; In toluene;
DOI:10.1016/S0040-4039(00)85704-4

Reference yield:

: 53036-80-9
6-carboxy hexylidene triphenylphosphorane

: 85593-71-1
(2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 60 percent / tetrahydrofuran; hexamethylphosphoric acid triamide / -78 °C

2: 80 percent / LiAlH₄ / tetrahydrofuran / Heating

3: TFA / tetrahydrofuran; H₂O / 16 h / Ambient temperature

5: 50 percent / benzene / 6 h / 80 °C

6: 80 percent / DMAP, Et₃N / CH₂Cl₂

7: 90 percent / NaH / toluene

With dmap; lithium aluminium tetrahydride; sodium hydride; triethylamine; trifluoroacetic acid; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane; water; toluene; benzene;
DOI:10.1016/S0040-4039(00)85704-4

Reference yield:

: 85593-68-6
(Z)-(R)-2-(tert-Butyl-diphenyl-silanyloxy)-10-hydroxy-dec-4-enal

: 85593-71-1
(2E,4E,8Z)-(R)-6,14-Bis-(tert-butyl-diphenyl-silanyloxy)-tetradeca-2,4,8-trienoic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 50 percent / benzene / 6 h / 80 °C

2: 80 percent / DMAP, Et₃N / CH₂Cl₂

3: 90 percent / NaH / toluene

With dmap; sodium hydride; triethylamine; In dichloromethane; toluene; benzene;
DOI:10.1016/S0040-4039(00)85704-4