Benzyl 4-(3-hydroxypropyl)piperidine-1-carboxylate

Base Information

Chemical Name:Benzyl 4-(3-hydroxypropyl)piperidine-1-carboxylate
CAS No.:99198-80-8
Molecular Formula:C16H23 N O3
Molecular Weight:277.364
Hs Code.:2933399090
DSSTox Substance ID:DTXSID50566621
Wikidata:Q82452314
Mol file:99198-80-8.mol

Synonyms:99198-80-8;Benzyl 4-(3-hydroxypropyl)piperidine-1-carboxylate;1-CBZ-4-(3-HYDROXY-PROPYL)-PIPERIDINE;1-Cbz-4-(3-hydroxypropyl)piperidine;Benzyl4-(3-hydroxypropyl)piperidine-1-carboxylate;SCHEMBL7107231;DTXSID50566621;LQEJJAZXQQCBBT-UHFFFAOYSA-N;MFCD04973406;1-Cbz-4-(3-Hydroxypropyl)-piperidine;AB21331;AM101778;3-(1-Benzyloxycarbonyl-4-piperidyl)propanol;CS-0130565;F71724;EN300-7234362;A845977;A1-19941;(phenylmethyl) 4-(3-hydroxypropyl)-1-piperidinecarboxylate;4-(3-hydroxypropyl)piperidine-1-carboxylic acid benzyl ester

Suppliers and Price of Benzyl 4-(3-hydroxypropyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
1-Cbz-4-(3-Hydroxy-propyl)-piperidine 97%
1g
$ 598.00

Crysdot
Benzyl4-(3-hydroxypropyl)piperidine-1-carboxylate 95+%
1g
$ 455.00

Chemenu
1-Cbz-4-(3-Hydroxy-propyl)-piperidine 95%
1g
$ 430.00

American Custom Chemicals Corporation
1-CBZ-4-(3-HYDROXY-PROPYL)-PIPERIDINE 97.00%
5MG
$ 498.63

Alichem
Benzyl4-(3-hydroxypropyl)piperidine-1-carboxylate
1g
$ 401.76

Activate Scientific
1-Cbz-4-(3-hydroxypropyl)piperidine 97%
1 g
$ 400.00

Acrotein
1-Cbz-4-(3-hydroxypropyl)piperidine 97%
0.5g
$ 201.67

A1 Biochem Labs
1-Cbz-4-(3-Hydroxy-propyl)-piperidine 95%
5 g
$ 1250.00

Total 12 raw suppliers

Chemical Property of Benzyl 4-(3-hydroxypropyl)piperidine-1-carboxylate

Chemical Property:

PSA：49.77000
LogP:2.74560
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:277.16779360
Heavy Atom Count:20
Complexity:281

Purity/Quality:

97% ^*data from raw suppliers

1-Cbz-4-(3-Hydroxy-propyl)-piperidine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1CCCO)C(=O)OCC2=CC=CC=C2

Technology Process of Benzyl 4-(3-hydroxypropyl)piperidine-1-carboxylate

There total 3 articles about Benzyl 4-(3-hydroxypropyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 7037-49-2
3-(piperidin-4-yl)propan-1-ol

: 501-53-1,94274-21-2
benzyl chloroformate

: 99198-80-8
benzyl 4-(2-hydroxypropyl)-1-piperidinecarboxylate

Guidance literature:: With triethylamine; In dichloromethane; for 1.75h; Ambient temperature;
DOI:10.1248/cpb.34.3747

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 156185-63-6
N-Boc-piperidin-4-yl-propanol

: 99198-80-8
benzyl 4-(2-hydroxypropyl)-1-piperidinecarboxylate

Guidance literature:: N-Boc-piperidin-4-yl-propanol; With hydrogenchloride; In methanol; dichloromethane; at 20 ℃; for 2h;

benzyl chloroformate; With sodium hydrogencarbonate; In tetrahydrofuran; at 0 ℃; for 1h;