α-hydrazinobenzenepropanoic acid

Base Information

• Chemical Name: α-hydrazinobenzenepropanoic acid
• CAS No.: 1421-34-7
• Molecular Formula: C₉H₁₂N₂O₂
• Molecular Weight: 180.206
• Mol file: 1421-34-7.mol

Synonyms:α-hydrazinobenzenepropanoic acid

Chemical Property of α-hydrazinobenzenepropanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-hydrazinobenzenepropanoic acid

There total 9 articles about α-hydrazinobenzenepropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sulfuric acid (7664-93-9) + 2-benzylidenehydrazino-3-phenyl-propionic acid → α-hydrazinobenzenepropanoic acid (1421-34-7,13079-06-6) + benzaldehyde (100-52-7)

Guidance literature:

DOI:10.1016/S0272-6386(00)70042-4

Reference yield:

2-diazo-3-phenyl-propionic acid ethyl ester (15626-54-7) → α-hydrazinobenzenepropanoic acid (1421-34-7,13079-06-6)

Guidance literature:

With sodium amalgam; In ethanol;

DOI:10.1248/cpb.24.800

Reference yield:

2-Hydrazono-3-phenylpropionsaeureaethylester (60030-15-1) → α-hydrazinobenzenepropanoic acid (1421-34-7,13079-06-6)

Guidance literature:

With sodium amalgam; In ethanol;

DOI:10.1248/cpb.24.800

upstream raw materials:

2-bromo-3-phenylpropanoic acid

2-diazo-3-phenyl-propionic acid ethyl ester

2-Hydrazono-3-phenylpropionsaeureaethylester

2-(N,N'-Diacetyl-hydrazino)-3-phenyl-propionic acid ethyl ester

Downstream raw materials:

α-[2-(aminoiminomethyl)hydrazino]benzenepropanoic acid monohydrate

phenyllactic acid

2-hydrazino-3-phenyl-propionic acid ethyl ester

Refernces

• 1、 Takamuta,Yamada. "Amino acids and peptides. XX. Reduction of α substituted α diazo esters. Convenient synthesis of α hydrazinocarboxylic acids and their derivatives from α amino acids". . p. 800 - 803. Retrieved 2007/10/05.