(benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-N^G-nitroargininal semicarbazone

Base Information

• Chemical Name: (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-N^G-nitroargininal semicarbazone
• CAS No.: 122314-22-1
• Molecular Formula: C₃₀H₄₂N₁₀O₇
• Molecular Weight: 654.726
• Mol file: 122314-22-1.mol

Synonyms:(benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-N^G-nitroargininal semicarbazone

Chemical Property of (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-N^G-nitroargininal semicarbazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-N^G-nitroargininal semicarbazone

There total 2 articles about (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-N^G-nitroargininal semicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C26H32N2O7 + NG-nitro-L-argininal semicarbazone trifluoroacetate (122314-15-2) → (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-NG-nitroargininal semicarbazone (122314-22-1)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 0 ℃; for 3h; Yield given;

DOI:10.1021/jm00163a014

Reference yield:

N-benzyloxycarbonyl-L-leucyl-L-phenylalanine (6401-63-4) → (benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-NG-nitroargininal semicarbazone (122314-22-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Et₃N / 1.) DMF, -15 deg C, 30 min, 2.) DMF, -15 deg C, 45 min

2: triethylamine / dimethylformamide / a) 0 deg C, 4 h, b) RT, overnight

With triethylamine; In N,N-dimethyl-formamide;

DOI:10.1021/jm00060a016

Reference yield:

(benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-NG-nitroargininal semicarbazone (122314-22-1) → C22H37N9O3*ClH

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; for 18h;

DOI:10.1021/jm00163a014

upstream raw materials:

N^G-nitro-L-argininal semicarbazone trifluoroacetate

N-benzyloxycarbonyl-L-leucyl-L-phenylalanine

Downstream raw materials:

(benzyloxycarbonyl)-L-leucyl-L-phenylalanyl-L-argininal hydrochloride