N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-3-(m-tolyl)propanamide

Base Information

• Chemical Name: N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-3-(m-tolyl)propanamide
• CAS No.: 1638490-41-1
• Molecular Formula: C₁₇H₁₂F₇NO
• Molecular Weight: 379.277
• Mol file: 1638490-41-1.mol

Synonyms:N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-3-(m-tolyl)propanamide

Chemical Property of N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-3-(m-tolyl)propanamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-3-(m-tolyl)propanamide

There total 2 articles about N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-3-(m-tolyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Iodotoluene (625-95-6) + N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)propionamide (1425052-35-2) → N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-3-(m-tolyl)propanamide (1638490-41-1)

Guidance literature:

With dipotassium hydrogenphosphate; palladium diacetate; silver carbonate; In 1,2-dichloro-ethane; at 100 ℃; for 24h; Sealed tube;

DOI:10.1002/anie.201403878

Reference yield:

→ N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-3-(m-tolyl)propanamide (1638490-41-1)

Guidance literature:

With oxalyl dichloride; In dichloromethane;

In dichloromethane; toluene; Reflux;

Reference yield: 68.0%

iodobenzene (591-50-4) + N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)-3-(m-tolyl)propanamide (1638490-41-1) → 6-methyl-4-phenyl-1-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)quinolin-2(1H)-one

Guidance literature:

With 2,5-dimethylpyridine; silver carbonate; palladium dichloride; In tert-Amyl alcohol; at 140 ℃; for 24h;

DOI:10.1002/anie.201403878

upstream raw materials:

3-Iodotoluene

N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)propionamide