Benzyl-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine

Base Information

• Chemical Name: Benzyl-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine
• CAS No.: 115867-16-8
• Molecular Formula: C₁₇H₂₉NOSi
• Molecular Weight: 291.509
• Mol file: 115867-16-8.mol

Synonyms:Benzyl-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine

Chemical Property of Benzyl-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzyl-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine

There total 4 articles about Benzyl-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-Benzylamino-3-buten-1-ol (50838-63-6,53214-59-8) + tert-butyldimethylsilyl chloride (18162-48-6) → Benzyl-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine (115867-16-8)

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; 0 deg C, 30 min then r.t., 3 h;

DOI:10.1016/0040-4039(94)88505-2

Reference yield:

benzoyl chloride (98-88-4) → Benzyl-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine (115867-16-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 50 percent / NaHCO₃ / H₂O; CH₂Cl₂ / 0.5 h / Ambient temperature

2: 93 percent / LiAlH₄ / diethyl ether / 14 h / Heating

3: 99 percent / imidazole / dimethylformamide / 0 deg C, 30 min then r.t., 3 h

With 1H-imidazole; lithium aluminium tetrahydride; sodium hydrogencarbonate; In diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1016/0040-4039(94)88505-2

Reference yield:

N-benzoyl vinyl glycine methyl ester (119768-88-6) → Benzyl-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine (115867-16-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / LiAlH₄ / diethyl ether / 14 h / Heating

2: 99 percent / imidazole / dimethylformamide / 0 deg C, 30 min then r.t., 3 h

With 1H-imidazole; lithium aluminium tetrahydride; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1016/0040-4039(94)88505-2

upstream raw materials:

2-Benzylamino-3-buten-1-ol

tert-butyldimethylsilyl chloride

benzoyl chloride

N-benzoyl vinyl glycine methyl ester

Downstream raw materials:

benzyl-<1-(tert.-butyldimethylsilyloxymethyl)-allyl>-(2-propinyl)-amine

2-Benzyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-2,3,3a,4,5,7a-hexahydro-isoindol-1-one

(3aR,7aS)-2-Benzyl-3-(tert-butyl-dimethyl-silanyloxymethyl)-2,3,3a,4,5,7a-hexahydro-1H-isoindole

Benzyl-(2-bromo-benzyl)-[1-(tert-butyl-dimethyl-silanyloxymethyl)-allyl]-amine