1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid

Base Information

Chemical Name:1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid
CAS No.:956011-26-0
Molecular Formula:C₁₄H₁₀FN₃O₂
Molecular Weight:271.251
Hs Code.:
UNII:2EUD88K9VR

Synonyms:1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid;956011-26-0;1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carboxylic acid;1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylicacid;2EUD88K9VR;SCHEMBL174160;QOMRCMAKWINLAN-UHFFFAOYSA-N;1-[(2-Fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid;1H-Pyrazolo[3,4-b]pyridine-3-carboxylic acid, 1-[(2-fluorophenyl)methyl]-

Suppliers and Price of 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 5 raw suppliers

Chemical Property of 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:271.07570473
Heavy Atom Count:20
Complexity:368

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CN2C3=C(C=CC=N3)C(=N2)C(=O)O)F

Technology Process of 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid

There total 1 articles about 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 256376-59-7
ethyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylate

: 956011-26-0
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid

Guidance literature:: ethyl 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylate; With water; sodium hydroxide; In 1,4-dioxane; at 20 ℃; for 2h;

With hydrogenchloride; In 1,4-dioxane; water;

Reference yield: 68.0%

: 956011-26-0
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid

: 1668-10-6
glycinamide hydrochloride

: 956011-25-9
N-(2-Amino-2-oxoethyl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

Guidance literature:: With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 20h;

Reference yield: 23.0%

: 16357-69-0
4-amino-5-cyanopyrimidine

: 956011-26-0
1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid

: 1361570-42-4
N-(5-cyanopyrimidin-4-yl)-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide

Guidance literature:: 1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid; With thionyl chloride; at 20 ℃; for 2h; Reflux;

4-amino-5-cyanopyrimidine; With pyridine; at 20 ℃; for 7h;