(S)-ethyl 2-((6-methylpyridin-2-yl)amino)-3-phenylpropanoate

Base Information

• Chemical Name: (S)-ethyl 2-((6-methylpyridin-2-yl)amino)-3-phenylpropanoate
• CAS No.: 1448586-29-5
• Molecular Formula: C₁₇H₂₀N₂O₂
• Molecular Weight: 284.358
• Mol file: 1448586-29-5.mol

Synonyms:(S)-ethyl 2-((6-methylpyridin-2-yl)amino)-3-phenylpropanoate

Chemical Property of (S)-ethyl 2-((6-methylpyridin-2-yl)amino)-3-phenylpropanoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (S)-ethyl 2-((6-methylpyridin-2-yl)amino)-3-phenylpropanoate

There total 1 articles about (S)-ethyl 2-((6-methylpyridin-2-yl)amino)-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

6-chloro-2-picoline (18368-63-3) + H-Phe-OEt (3081-24-1) → (S)-ethyl 2-((6-methylpyridin-2-yl)amino)-3-phenylpropanoate (1448586-29-5)

Guidance literature:

With palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In 1,4-dioxane; at 100 ℃; for 3h; Inert atmosphere;

DOI:10.1021/jo4011427

Reference yield:

(S)-ethyl 2-((6-methylpyridin-2-yl)amino)-3-phenylpropanoate (1448586-29-5) + (S)-Mosher acid (17257-71-5,20445-31-2,56135-03-6,81655-41-6) → C10H8F3O3(1-)*C17H20N2O2

Guidance literature:

In chloroform-d1;

DOI:10.1021/jo4011427

upstream raw materials:

6-chloro-2-picoline

H-Phe-OEt