Technology Process of 1,5-di(2-azidophenyl)naphthalene
There total 3 articles about 1,5-di(2-azidophenyl)naphthalene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
1-azido-2-iodo-benzene;
With
tetrakis(triphenylphosphine) palladium(0);
In
1,2-dimethoxyethane;
at 20 ℃;
for 0.25h;
Inert atmosphere;
2,2'-(naphthalene-1,5-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane);
With
sodium carbonate;
In
1,2-dimethoxyethane; ethanol;
for 8h;
Inert atmosphere;
Reflux;
DOI:10.1039/c2tc00363e
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium iodide; sodium nitrite; sulfuric acid / water / Inert atmosphere
2.1: n-butyllithium / diethyl ether / 7 h / -78 - -10 °C / Inert atmosphere
2.2: -78 - 20 °C / Inert atmosphere
3.1: tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane / 0.25 h / 20 °C / Inert atmosphere
3.2: 8 h / Inert atmosphere; Reflux
With
tetrakis(triphenylphosphine) palladium(0); n-butyllithium; sulfuric acid; potassium iodide; sodium nitrite;
In
1,2-dimethoxyethane; diethyl ether; water;
1.1: |Sandmeyer Reaction / 3.1: |Suzuki-Miyaura Coupling / 3.2: |Suzuki-Miyaura Coupling;
DOI:10.1039/c2tc00363e
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / diethyl ether / 7 h / -78 - -10 °C / Inert atmosphere
1.2: -78 - 20 °C / Inert atmosphere
2.1: tetrakis(triphenylphosphine) palladium(0) / 1,2-dimethoxyethane / 0.25 h / 20 °C / Inert atmosphere
2.2: 8 h / Inert atmosphere; Reflux
With
tetrakis(triphenylphosphine) palladium(0); n-butyllithium;
In
1,2-dimethoxyethane; diethyl ether;
2.1: |Suzuki-Miyaura Coupling / 2.2: |Suzuki-Miyaura Coupling;
DOI:10.1039/c2tc00363e
