Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester

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Chemical Name:Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester
CAS No.:200264-32-0
Molecular Formula:C₃₅H₃₃N₅O₁₁
Molecular Weight:699.674
Hs Code.:

Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester

Synonyms:Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester

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Chemical Property of Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester

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Technology Process of Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester

There total 5 articles about Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 110522-71-9
N²-phenoxyacetyl-2’-deoxyguanosine

: Imidazole-1-carboxylic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester; compound with trifluoro-methanesulfonic acid

: 200264-32-0
Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester

Guidance literature:: With pyridine; at 25 ℃;
DOI:10.1021/jo970872s

Reference yield:

: 701-99-5
Phenoxyacetyl chloride

: 200264-32-0
Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: acetonitrile

2: 1.) pyridine, trimethylsilyl chloride, 2.) pyridine / 1.) 25 deg C, 1 h, 2.) CH₃CN, 25 deg C

3: 56 percent / pyridine / 25 °C

With pyridine; chloro-trimethyl-silane; In acetonitrile;
DOI:10.1021/jo970872s

Reference yield:

: 188924-61-0
(3',5'-dimethoxyphenyl)phenylethane-1,2-dione

: 200264-32-0
Carbonic acid 1-(3,5-dimethoxy-phenyl)-2-oxo-2-phenyl-ethyl ester (2R,3S,5R)-3-hydroxy-5-[6-oxo-2-(2-phenoxy-acetylamino)-1,6-dihydro-purin-9-yl]-tetrahydro-furan-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: nitromethane / 3 h / 25 °C

2: 56 percent / pyridine / 25 °C

With pyridine; In nitromethane;
DOI:10.1021/jo970872s