7-Chloro-4-iodoquinoline

Base Information

• Chemical Name: 7-Chloro-4-iodoquinoline
• CAS No.: 98591-57-2
• Molecular Formula: C9H5 Cl I N
• Molecular Weight: 289.503
• Hs Code.: 2933499090
• European Community (EC) Number: 626-766-1
• DSSTox Substance ID: DTXSID20458100
• Nikkaji Number: J2.034.743K
• Wikidata: Q82281243
• Mol file: 98591-57-2.mol

Synonyms:7-Chloro-4-iodoquinoline;98591-57-2;7-chloro-4-iodo-quinoline;4-Iodo-7-chloroquinoline;SCHEMBL365024;DTXSID20458100;7-Chloro-4-iodoquinoline, 97%;HUTDAIDVAMQWDX-UHFFFAOYSA-N;YDA59157;AKOS015897215;AT14803;SB68644;BS-23450;AM20061654;7-CHLORO-4-IODOQUINOLINE, PURUM, 97%;EN300-2275080;A935370

Chemical Property of 7-Chloro-4-iodoquinoline

Chemical Property:

• Vapor Pressure: 6.67E-05mmHg at 25°C
• Melting Point: 125-129 °C(lit.)
• Refractive Index: 1.726
• Boiling Point: 354.8ºC at 760 mmHg
• Flash Point: 168.4ºC
• PSA: 12.89000
• Density: 1.919g/cm3
• LogP: 3.49280
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 288.91552
• Heavy Atom Count: 12
• Complexity: 165

Purity/Quality:

98%,99%, ^*data from raw suppliers

7-Chloro-4-iodoquinoline 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=CN=C2C=C1Cl)I
• Uses: 7-Chloro-4-iodoquinoline is used as a quinolinic-isoquinolinic derivative for acting as reversible electrochromes.

Technology Process of 7-Chloro-4-iodoquinoline

There total 4 articles about 7-Chloro-4-iodoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4,7-dichloroquinoline (86-98-6,1138471-54-1) → 7-chloro-4-iodoquinoline (98591-57-2)

Guidance literature:

With acetic anhydride; sodium iodide; In acetonitrile; at 18 - 80 ℃; Microwave irradiation;

DOI:10.1021/jo9008386

Reference yield:

4,7-dichloroquinoline (86-98-6,1138471-54-1) + water (7732-18-5) → 7-chloro-4-iodoquinoline (98591-57-2)

Guidance literature:

With sodium hydroxide; HI;

Reference yield:

4,7-dichloroquinoline hydrochloride → 7-chloro-4-iodoquinoline (98591-57-2)

Guidance literature:

With sodium iodide; In acetonitrile; at 80 ℃; for 24h;

DOI:10.1055/s-2003-41405

upstream raw materials:

4,7-dichloroquinoline

hydrogen iodide

water

Downstream raw materials:

7-chloro-4-(4-fluorophenyl)quinoline

7-chloro-4-(3-fluorophenyl)quinoline

4,7-diphenylquinoline

7-chloro-(4-phenyl)quinoline