C₃₇H₄₅N₅O₈

Base Information

• Chemical Name: C₃₇H₄₅N₅O₈
• CAS No.: 1416726-89-0
• Molecular Formula: C₃₇H₄₅N₅O₈
• Molecular Weight: 687.793
• Mol file: 1416726-89-0.mol

Synonyms:C₃₇H₄₅N₅O₈

Chemical Property of C₃₇H₄₅N₅O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₇H₄₅N₅O₈

There total 3 articles about C₃₇H₄₅N₅O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

methyl (3R)-aminopentanoate (51220-50-9) + N2,N6-bis(3-phenylpropanoic acid-2-yl)pyridine-2,6-dicarboxamide (158946-78-2) → C37H45N5O8 (1416726-89-0)

Guidance literature:

N²,N⁶-bis(3-phenylpropanoic acid-2-yl)pyridine-2,6-dicarboxamide; With 4-methyl-morpholine; chloroformic acid ethyl ester; In dichloromethane; at -15 ℃; for 0.166667h;

methyl (3R)-aminopentanoate; In dichloromethane; at -15 - 20 ℃; for 15h;

DOI:10.5560/ZNB.2012-0116

Reference yield:

Pyridine-2,6-dicarboxylic acid (499-83-2) → C37H45N5O8 (1416726-89-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: chloroformic acid ethyl ester; 4-methyl-morpholine / dichloromethane / 0.17 h / -15 °C

1.2: 15 h / -15 - 20 °C

2.1: sodium hydroxide; water / methanol / 5 h / -5 - 20 °C

3.1: chloroformic acid ethyl ester; 4-methyl-morpholine / dichloromethane / 0.17 h / -15 °C

3.2: 15 h / -15 - 20 °C

With 4-methyl-morpholine; water; chloroformic acid ethyl ester; sodium hydroxide; In methanol; dichloromethane;

DOI:10.5560/ZNB.2012-0116

Reference yield:

methyl (2S)-2-amino-3-phenylpropanoate (2577-90-4) → C37H45N5O8 (1416726-89-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: chloroformic acid ethyl ester; 4-methyl-morpholine / dichloromethane / 0.17 h / -15 °C

1.2: 15 h / -15 - 20 °C

2.1: sodium hydroxide; water / methanol / 5 h / -5 - 20 °C

3.1: chloroformic acid ethyl ester; 4-methyl-morpholine / dichloromethane / 0.17 h / -15 °C

3.2: 15 h / -15 - 20 °C

With 4-methyl-morpholine; water; chloroformic acid ethyl ester; sodium hydroxide; In methanol; dichloromethane;

DOI:10.5560/ZNB.2012-0116

upstream raw materials:

methyl (3R)-aminopentanoate

N²,N⁶-bis(3-phenylpropanoic acid-2-yl)pyridine-2,6-dicarboxamide

Pyridine-2,6-dicarboxylic acid

methyl (2S)-2-amino-3-phenylpropanoate

Downstream raw materials:

C₃₅H₄₁N₅O₈

C₄₂H₅₃N₇O₈

C₄₁H₅₁N₇O₈

C₄₁H₅₃N₉O₇