(S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal

Base Information

• Chemical Name: (S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal
• CAS No.: 85148-24-9
• Molecular Formula: C₁₆H₂₄O₄
• Molecular Weight: 280.364
• Mol file: 85148-24-9.mol

Synonyms:(S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal

Chemical Property of (S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal

There total 3 articles about (S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

methyl magnesium iodide (917-64-6) + 3-(2,5-Dimethoxy-3,4,6-trimethyl-phenyl)-1-((S)-2-phenyl-hexahydro-pyrrolo[1,2-c]imidazol-3-yl)-propan-1-one (85148-23-8) → (S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal (85148-24-9) + (2S)-2-(anilinomethyl)pyrrolidine (64030-44-0)

Guidance literature:

With hydrogenchloride; Yield given. Multistep reaction; 1.)-100 deg C 2.) 0 deg C;

DOI:10.1016/S0040-4039(00)85757-3

Reference yield:

C13H19MgO2(1+) → (S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal (85148-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 55 percent / -100 °C

2: 2.) 2percent hydrochoric acid / 1.)-100 deg C 2.) 0 deg C

With hydrogenchloride;

DOI:10.1016/S0040-4039(00)85757-3

Reference yield:

→ (S)-4-(2,5-dimethoxy-3,4,6-trimethylphenyl)-2-hydroxy-2-methylbutanal (85148-24-9)

Guidance literature:

upstream raw materials:

methyl magnesium iodide

3-(2,5-Dimethoxy-3,4,6-trimethyl-phenyl)-1-((S)-2-phenyl-hexahydro-pyrrolo[1,2-c]imidazol-3-yl)-propan-1-one

Downstream raw materials:

(S)-4-<2-(2,5-dimethoxy-3,4,6-trimethylphenyl)ethyl>-2,2,4-trimethyl-1,3-dioxorane

(S)-2-methyl-4-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-butane-1,2-diol

(S)-4-(2',5'-dimethoxy-3',4',6'-trimethylphenyl)-2-methyl-1,2-butanediol