1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)-3-(4-methoxyphenyl)propenone

Base Information

• Chemical Name: 1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)-3-(4-methoxyphenyl)propenone
• CAS No.: 909781-66-4
• Molecular Formula: C₂₆H₂₈O₄
• Molecular Weight: 404.506
• Mol file: 909781-66-4.mol

Synonyms:1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)-3-(4-methoxyphenyl)propenone

Chemical Property of 1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)-3-(4-methoxyphenyl)propenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)-3-(4-methoxyphenyl)propenone

There total 5 articles about 1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)-3-(4-methoxyphenyl)propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)ethanone (31771-72-9) + 4-methoxy-benzaldehyde (123-11-5) → 1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)-3-(4-methoxyphenyl)propenone (909781-66-4)

Guidance literature:

With potassium hydroxide; In ethanol; at 20 ℃; for 48h;

DOI:10.1016/j.bmc.2005.07.005

Reference yield:

2',4'-dihydroxy-4-acetophenone (89-84-9) → 1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)-3-(4-methoxyphenyl)propenone (909781-66-4)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 7 h / 150 °C

2: 50 percent / aq. KOH / ethanol / 48 h / 20 °C

With pyridine; potassium hydroxide; In ethanol; 2: Claisen-Schmidt condensation;

DOI:10.1016/j.bmc.2005.07.005

Reference yield:

(Z)-1,1-dimethoxy-3,7-dimethylocta-2,6-diene (75128-97-1) → 1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)-3-(4-methoxyphenyl)propenone (909781-66-4)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 7 h / 150 °C

2: 50 percent / aq. KOH / ethanol / 48 h / 20 °C

With pyridine; potassium hydroxide; In ethanol; 2: Claisen-Schmidt condensation;

DOI:10.1016/j.bmc.2005.07.005

upstream raw materials:

1-(5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromen-6-yl)ethanone

4-methoxy-benzaldehyde

5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromene-6-carboxylic acid

5-hydroxy-2-methyl-2-(4-methylpent-3-enyl)-2H-chromene-6-carboxylic acid ethyl ester